Cellosaurus cell line I 3 (CVCL

Cellosaurus I 3 (CVCL_C376)

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Cell line name

I 3

Synonyms

I3; Israel number 3; TE03; TE-03; ES-I3; hES I3; HESI3; TECHe001-A

Accession

CVCL_C376

Resource Identification Initiative

To cite this cell line use: I 3 (RRID:CVCL_C376)

Comments

From: Technion - Israel Institute of Technology; Haifa; Israel.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-13-0204.
Registration: Swiss research registry; BAG-hES-IMP-0005.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K36me3.
Omics: Genomics; ChIP-seq; H3K4me1.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; ChIP-seq; H3K9ac.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_C377 (I 3.2)

CVCL_C378 (I 3.3)

Sex of cell

Female

Age at sampling

Blastocyst stage

Category

Embryonic stem cell

STR profile

Source(s): PubMed=16919167; WiCell=te03

Markers:

Amelogenin	X
CSF1PO	11,12
D5S818	11,12
D7S820	10,11
D13S317	12,14
D16S539	11,12
TH01	7,9
TPOX	8
vWA	16,17

Web pages

Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/affy/8
Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/Agilent/8

Publications

PubMed=16919167; DOI=10.1186/1741-7007-4-28; PMCID=PMC1601965
Richard Josephson, Gregory R. Sykes, Ying Liu, Carol J. Ording, Wei-Ning Xu, Xian-Min Zeng, Soojung Shin, Jeanne Frances Loring, Anirban Maitra, Mahendra Surendra Rao, Jonathan M. Auerbach;
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=17572666; DOI=10.1038/nbt1318
Oluseun Adewumi, Behrouz Aflatoonian, Lars Ahrlund-Richter, Michal Amit, Peter W. Andrews, Gemma Beighton, Paul A. Bello, Nissim Benvenisty, Lorraine S. Berry, Simon Bevan, Barak Blum ...Show all 85 authors... , Justin Brooking, Kevin Gang Chen, Andre B.-H. Choo, Gary Allen Churchill, Marie Corbel, Ivan Damjanov, Jonathan S. Draper, Petr Dvorak, Katarina Emanuelsson, Roland A. Fleck, Angela Ford, Karin Gertow, Marina Gertsenstein, Paul J. Gokhale, Rebecca S. Hamilton, Ales Hampl, Lyn E. Healy, Outi Hovatta, Johan Hyllner, Marta P. Imreh, Joseph Itskovitz-Eldor, Jamie Jackson, Jacqueline L. Johnson, Mark Jones, Kehkooi Kee, Benjamin L. King, Barbara B. Knowles, Majlinda Lako, Franck Lebrin, Barbara S. Mallon, Daisy Manning, Yoav Mayshar, Ronald Davies Graham McKay, Anna E. Michalska, Milla Mikkola, Maria Mileikovsky, Stephen Lewis Minger, Harry D. Moore, Christine Lindsay Mummery, Andras Nagy, Norio Nakatsuji, Carmel M. O'Brien, Steve Kah-Weng Oh, Cia Olsson, Timo Otonkoski, Kye-Yoon Park, Robert Passier, Hema Patel, Minal J. Patel, Roger Arnold Pedersen, Martin F. Pera, Marian S. Piekarczyk, Renee A. Reijo Pera, Benjamin E. Reubinoff, Allan J. Robins, Janet Rossant, Peter Rugg-Gunn, Thomas C. Schulz, Henrik Semb, Eric S. Sherrer, Henrike Siemen, Glyn N. Stacey, Miodrag Stojkovic, Hirofumi Suemori, Jin Szatkiewicz, Tikva Tako Turetsky, Timo Tuuri, Stieneke van den Brink, Kristina Vintersten, Sanna Vuoristo, Dorien Ward-van Oostwaard, Thomas A. Weaver, Lesley A. Young, Wei-Dong Zhang; Show fewer authors
International Stem Cell Initiative
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=23117585; DOI=10.1016/j.scr.2012.09.002; PMCID=PMC3590800
Barbara S. Mallon, Joshua G. Chenoweth, Kory R. Johnson, Rebecca S. Hamilton, Paul J. Tesar, Amarendra S. Yavatkar, Leonard J. Tyson, Kyeyoon Park, Kevin Gang Chen, Yang-Cheng Fann, Ronald Davies Graham McKay;
StemCellDB: the human pluripotent stem cell database at the National Institutes of Health.
Stem Cell Res. 10:57-66(2013)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references

Cell line collections (Providers)

WiCell; te03

Cell line databases/resources

hPSCreg; TECHe001-A
IGRhCellID; I3%20p41
NIHhESC; NIHhESC-13-0204
SKIP; SKIP001859

Anatomy/cell type resources

BTO; BTO_0006059

Biological sample resources

BioSample; SAMN03471893
ENCODE; ENCBS057COO
ENCODE; ENCBS058LJQ
ENCODE; ENCBS065EQG
ENCODE; ENCBS224XQX
ENCODE; ENCBS268NCC
ENCODE; ENCBS312JDV
ENCODE; ENCBS401QZO
ENCODE; ENCBS412HHB
ENCODE; ENCBS421TWG
ENCODE; ENCBS433JWB
ENCODE; ENCBS524MEF
ENCODE; ENCBS533SYQ
ENCODE; ENCBS593HOC
ENCODE; ENCBS599JGY
ENCODE; ENCBS682JTI
ENCODE; ENCBS811OSD

Encyclopedic resources

Wikidata; Q54897060

Experimental variables resources

EFO; EFO_0007076

Gene expression databases

GEO; GSM537624
GEO; GSM537625
GEO; GSM537626
GEO; GSM537627
GEO; GSM537647
GEO; GSM537648
GEO; GSM537664
GEO; GSM537665
GEO; GSM537668
GEO; GSM537669
GEO; GSM537670
GEO; GSM537672
GEO; GSM621345
GEO; GSM621348
GEO; GSM621386
GEO; GSM772789
GEO; GSM856736
GEO; GSM981282
GEO; GSM981293
GEO; GSM1342462
GEO; GSM1342464

Entry history

Entry creation

22-Oct-2012

Last entry update

10-Apr-2025

Version number