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Cellosaurus OMM2.3 (CVCL_C306)

[Text version]
Cell line name OMM2.3
Synonyms Omm2.3; OMM2_3; OMM-2.3; OMM 2-3; OMM1.3; Omm1_3; OMM1_3
Accession CVCL_C306
Resource Identification Initiative To cite this cell line use: OMM2.3 (RRID:CVCL_C306)
Comments From: Ksander, Bruce R.; Schepens Eye Research Institute; Boston; USA.
Omics: Proteomics.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C302 ! Mel270
CVCL_C305 ! OMM2.2
CVCL_C307 ! OMM2.5
CVCL_C308 ! OMM2.6
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=22236444

Markers:
AmelogeninX,Y
CSF1PO11
D3S135816
D5S81812
D7S8208,9
D13S31712
D16S53912
FGA26
TH016,9
TPOX10
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=9247253; DOI=10.1023/A:1018479011340
Peter W. Chen, Timothy G. Murray, Toshihiko Uno, Michael L. Salgaller, Rajender Reddy, Bruce R. Ksander;
Expression of MAGE genes in ocular melanoma during progression from primary to metastatic disease.
Clin. Exp. Metastasis 15:509-518(1997)

PubMed=16772116; DOI=10.1016/j.cancergencyto.2005.11.016
Jason S. White, Robert L. Becker, Ian W. McLean, Alison E. Director-Myska, Joginder Nath;
Molecular cytogenetic evaluation of 10 uveal melanoma cell lines.
Cancer Genet. Cytogenet. 168:11-21(2006)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Klaus Georg Griewank, Xiao-Xing Yu, Jahan S. Khalili, Mustafa Mert Sozen, Katherine Stemke-Hale, Chantale Bernatchez, Seth Wardell, Boris C. Bastian, Scott E. Woodman;
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=28018010; PMCID=PMC5161001
Martine Johanna Jager, Jose Antonio Bermudez Magner, Bruce R. Ksander, Sander R. Dubovy;
Uveal melanoma cell lines: where do they come from? (an American Ophthalmological Society thesis).
Trans. Am. Ophthalmol. Soc. 114:T5-T5(2016)

PubMed=32430489; DOI=10.1158/1535-7163.MCT-19-1016; PMCID=PMC7415561
Jessica L.F. Teh, Timothy J. Purwin, Anna Han, Vivian Chua, Prem Patel, Usman Baqai, Connie Liao, Nelisa Bechtel, Takami Sato, Michael A. Davies, Julio A. Aguirre-Ghiso, Andrew E. Aplin;
Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal melanoma.
Mol. Cancer Ther. 19:1719-1726(2020)

PubMed=39042403; DOI=10.1167/iovs.65.8.37; PMCID=PMC11268447
Maria Chiara Gelmi, Arnoud H. de Ru, Peter A. van Veelen, Rayman T.N. Tjokrodirijo, Marc-Henri Stern, Alexandre Houy, Robert M. Verdijk, T.H. Khanh Vu, Bruce R. Ksander, Jolanda Vaarwater, Emine Kilic ...Show all 13 authors... , Erwin Brosens, Martine Johanna Jager; Show fewer authors
Protein and mRNA expression in uveal melanoma cell lines are related to GNA and BAP1 mutation status.
Invest. Ophthalmol. Vis. Sci. 65:37-37(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C306
Cell_Model_Passport; SIDM01844
Encyclopedic resources Wikidata; Q54936372
Polymorphism and mutation databases Cosmic; 899900
Cosmic; 916145
Cosmic; 1628397
Cosmic; 1669127
Cosmic; 2036705
Proteomic databases PRIDE; PXD051055
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number21