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Cellosaurus Mel290 (CVCL_C304)

[Text version]
Cell line name Mel290
Synonyms MEL290; Mel-290; Mel 290; MEL 290
Accession CVCL_C304
Resource Identification Initiative To cite this cell line use: Mel290 (RRID:CVCL_C304)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
From: Ksander, Bruce R.; Schepens Eye Research Institute; Boston; USA.
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): DepMap=ACH-002016; ICLC=HTL12002; PubMed=22236444

Markers:
AmelogeninX
CSF1PO10,11
D3S135815,18
D5S81810,12
D7S82011,12
D8S117911,13
D13S3178,11
D16S53911,13
D18S5114,15
D21S1128,32.1
FGA18,20
Penta D10,11
Penta E5,8
TH016,9
TPOX8,11
vWA14,16

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Publications

PubMed=16772116; DOI=10.1016/j.cancergencyto.2005.11.016
White J.S., Becker R.L., McLean I.W., Director-Myska A.E., Nath J.
Molecular cytogenetic evaluation of 10 uveal melanoma cell lines.
Cancer Genet. Cytogenet. 168:11-21(2006)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Griewank K.G., Yu X.-X., Khalili J.S., Sozen M.M., Stempke-Hale K., Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=22383533; DOI=10.1158/1535-7163.MCT-11-0676
Dutton-Regester K., Irwin D., Hunt P., Aoude L.G., Tembe V., Pupo G.M., Lanagan C., Carter C.D., O'Connor L., O'Rourke M., Scolyer R.A., Mann G.J., Schmidt C.W., Herington A., Hayward N.K.
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma.
Mol. Cancer Ther. 11:888-897(2012)

PubMed=23849826; DOI=10.1016/j.ejca.2013.06.011
Amaro A., Mirisola V., Angelini G., Musso A., Tosetti F.I., Esposito A.I., Perri P., Lanza F.B., Nasciuti F., Mosci C., Puzone R., Salvi S., Truini M., Poggi A., Pfeffer U.
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Eur. J. Cancer 49:3353-3365(2013)

PubMed=28018010; PMCID=PMC5161001
Jager M.J., Bermudez Magner J.A., Ksander B.R., Dubovy S.R.
Uveal melanoma cell lines: where do they come from? (an American Ophthalmological Society thesis).
Trans. Am. Ophthalmol. Soc. 114:T5-T5(2016)

Cross-references
Cell line collections (Providers) ICLC; HTL12002
Cell line databases/resources CLDB; cl7222
cancercelllines; CVCL_C304
Cell_Model_Passport; SIDM01792
DepMap; ACH-002016
Encyclopedic resources Wikidata; Q54905165
Polymorphism and mutation databases Cosmic; 916141
Cosmic; 1628406
Cosmic; 1669125
Entry history
Entry creation22-Oct-2012
Last entry update10-Sep-2024
Version number19