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Cellosaurus HeLa S3 penta KO-ULK1/ULK2 DKO (CVCL_C2VS)

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Cell line name HeLa S3 penta KO-ULK1/ULK2 DKO
Synonyms HeLa S3 ULK1/2 DKO/penta KO
Accession CVCL_C2VS
Resource Identification Initiative To cite this cell line use: HeLa S3 penta KO-ULK1/ULK2 DKO (RRID:CVCL_C2VS)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; 29912; CALCOCO2.
Knockout cell: Method=CRISPR/Cas9; HGNC; 6746; NBR1.
Knockout cell: Method=TALEN; HGNC; 17142; OPTN.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11280; SQSTM1.
Knockout cell: Method=CRISPR/Cas9; HGNC; 11575; TAX1BP1.
Knockout cell: Method=CRISPR/Cas9; HGNC; 12558; ULK1.
Knockout cell: Method=CRISPR/Cas9; HGNC; 13480; ULK2.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C2VN (HeLa S3 penta KO)
Children:
CVCL_C2VT (HeLa S3 penta KO-TBK1/ULK1/ULK2 TKO)CVCL_C9DW (HeLa S3 penta KO-ULK1/ULK2 DKO-AZI2/TBKBP1 DKO)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

DOI=10.1101/2023.09.25.559255
Adriaenssens E., Nguyen T.N., Sawa-Makarska J., Khuu G., Schuschnig M., Watts E.M., Shoebridge S., Csalyi K.D., Padman B.S., Lazarou M., Martens S.
Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD.
bioRxiv 2023:09.25.559255-09.25.559255(2023)

Cross-references
Encyclopedic resources Wikidata; Q114311589
Entry history
Entry creation22-Sep-2022
Last entry update30-Jan-2024
Version number6