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Cellosaurus BEAS-2B IRF1 KO (CVCL_C2UN)

[Text version]
Cell line name BEAS-2B IRF1 KO
Synonyms BEAS-2B-IRF1 KO; IRF1 KO BEAS-2B
Accession CVCL_C2UN
Resource Identification Initiative To cite this cell line use: BEAS-2B IRF1 KO (RRID:CVCL_C2UN)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:6116; IRF1.
Transformant: Ad12-SV40 hybrid virus.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0168 (BEAS-2B)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=31156620; DOI=10.3389/fimmu.2019.01019; PMCID=PMC6529937
Debasis Panda, Erisa Gjinaj, Mahesh Bachu, Erica Squire, Hilary Novatt, Keiko Ozato, Ronald L. Rabin;
IRF1 maintains optimal constitutive expression of antiviral genes and regulates the early antiviral response.
Front. Immunol. 10:1019.1-1019.16(2019)

Cross-references
Encyclopedic resources Wikidata; Q114310727
Gene expression databases GEO; GSM3138806
GEO; GSM3138807
GEO; GSM3138808
GEO; GSM3138809
GEO; GSM3138810
GEO; GSM3138811
GEO; GSM3138812
GEO; GSM3138813
GEO; GSM3138814
Entry history
Entry creation22-Sep-2022
Last entry update10-Apr-2025
Version number7