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Cellosaurus UPMM-1 (CVCL_C299)

[Text version]
Cell line name UPMM-1
Synonyms UPMM1; Uveal Primary Melanoma with Monosomy-3 1
Accession CVCL_C299
Resource Identification Initiative To cite this cell line use: UPMM-1 (RRID:CVCL_C299)
Comments Doubling time: 100-150 hours (PubMed=19212147).
Karyotypic information: Monosomy of chromosome 3 (PubMed=16750193).
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=22236444

Markers:
AmelogeninX,Y
CSF1PO10,12
D3S135818
D5S81811,12
D7S8208
D13S3179,11
D16S53913
FGA21
TH019,9.3
TPOX8,11
vWA15,16

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Publications

PubMed=16750193; DOI=10.1016/j.exer.2006.04.004
Gordon Nareyeck, Michael Zeschnigk, Gabriele Prescher, Dietmar R. Lohmann, Gerasimos Anastassiou;
Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3.
Exp. Eye Res. 83:858-864(2006)

PubMed=19212147; DOI=10.1159/000201566
Gordon Nareyeck, Michael Zeschnigk, Norbert Bornfeld, Gerasimos Anastassiou;
Novel cell lines derived by long-term culture of primary uveal melanomas.
Ophthalmologica 223:196-201(2009)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Klaus Georg Griewank, Xiao-Xing Yu, Jahan S. Khalili, Mustafa Mert Sozen, Katherine Stemke-Hale, Chantale Bernatchez, Seth Wardell, Boris C. Bastian, Scott E. Woodman;
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=23849826; DOI=10.1016/j.ejca.2013.06.011
Adriana Amaro, Valentina Mirisola, Giovanna Angelini, Alessandra Musso, Francesca Isabella Tosetti, Alessia Isabella Esposito, Patrizia Perri, Francesco Baldo Lanza, Francesca Nasciuti, Carlo Mosci, Roberto Puzone ...Show all 15 authors... , Sandra Salvi, Mauro Truini, Alessandro Poggi, Ulrich Pfeffer; Show fewer authors
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Eur. J. Cancer 49:3353-3365(2013)

Cross-references
Cell line collections (Providers) Kerafast; EDE001
Cell line databases/resources cancercelllines; CVCL_C299
Encyclopedic resources Wikidata; Q54991706
Polymorphism and mutation databases Cosmic; 1628399
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number16