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Cellosaurus UPMM-3 (CVCL_C295)

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Cell line name UPMM-3
Synonyms UPMM3; Uveal Primary Melanoma with Monosomy-3 3
Accession CVCL_C295
Resource Identification Initiative To cite this cell line use: UPMM-3 (RRID:CVCL_C295)
Comments Doubling time: 100 hours (PubMed=19212147).
Karyotypic information: Monosomy of chromosome 3 (PubMed=19212147).
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ICLC=HTL13001; PubMed=22236444

Markers:
AmelogeninX,Y
CSF1PO12,13
D5S81810,11
D7S8208,11
D13S3178,11
D16S53912
D21S1128,31.2
FGA19
TH017,9.3
TPOX9,10
vWA16,17

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Publications

PubMed=19212147; DOI=10.1159/000201566
Gordon Nareyeck, Michael Zeschnigk, Norbert Bornfeld, Gerasimos Anastassiou;
Novel cell lines derived by long-term culture of primary uveal melanomas.
Ophthalmologica 223:196-201(2009)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Klaus Georg Griewank, Xiao-Xing Yu, Jahan S. Khalili, Mustafa Mert Sozen, Katherine Stemke-Hale, Chantale Bernatchez, Seth Wardell, Boris C. Bastian, Scott E. Woodman;
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=23849826; DOI=10.1016/j.ejca.2013.06.011
Adriana Amaro, Valentina Mirisola, Giovanna Angelini, Alessandra Musso, Francesca Isabella Tosetti, Alessia Isabella Esposito, Patrizia Perri, Francesco Baldo Lanza, Francesca Nasciuti, Carlo Mosci, Roberto Puzone ...Show all 15 authors... , Sandra Salvi, Mauro Truini, Alessandro Poggi, Ulrich Pfeffer; Show fewer authors
Evidence of epidermal growth factor receptor expression in uveal melanoma: inhibition of epidermal growth factor-mediated signalling by gefitinib and cetuximab triggered antibody-dependent cellular cytotoxicity.
Eur. J. Cancer 49:3353-3365(2013)

Cross-references
Cell line collections (Providers) ICLC; HTL13001
Cell line databases/resources CLDB; cl7223
cancercelllines; CVCL_C295
Encyclopedic resources Wikidata; Q54991709
Polymorphism and mutation databases Cosmic; 1628401
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number19