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Cellosaurus Ma-Mel-59c (CVCL_C290)

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Cell line name Ma-Mel-59c
Accession CVCL_C290
Resource Identification Initiative To cite this cell line use: Ma-Mel-59c (RRID:CVCL_C290)
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23348503).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=23348503).
Disease Cutaneous nodular melanoma (NCIt: C4225)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A194 ! Ma-Mel-59a
CVCL_C289 ! Ma-Mel-59b
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-217

Markers:
AmelogeninX
CSF1PO10
D3S135817
D5S81812,13
D7S8208,12
D13S31712,13
FGA20,22
TH019
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=23348503; DOI=10.1126/science.1230062
Susanne Horn, Adina Figl, P. Sivaramakrishna Rachakonda, Christine Fischer, Antje Sucker, Andreas Gast, Stephanie Kadel, Iris Moll, Eduardo Nagore, Kari Hemminki, Dirk Schadendorf, Rajiv Kumar;
TERT promoter mutations in familial and sporadic melanoma.
Science 339:959-961(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C290
ESTDAB; ESTDAB-217
Encyclopedic resources Wikidata; Q54903826
Polymorphism and mutation databases Cosmic; 1846646
Cosmic; 2686441
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number16