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Cellosaurus Ma-Mel-54b (CVCL_C288)

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Cell line name Ma-Mel-54b
Accession CVCL_C288
Resource Identification Initiative To cite this cell line use: Ma-Mel-54b (RRID:CVCL_C288)
Comments Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Cutaneous; UBERON=UBERON_0000014.
Sequence variations
  • Mutation; HGNC; HGNC:6192; JAK2; Simple; p.Gln959Pro (c.2876A>C); Zygosity=Homozygous (PubMed=28561041).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A189 ! Ma-Mel-54a
Sex of cell Female
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-215

Markers:
AmelogeninX
CSF1PO12
D3S135814,16
D5S81812,13
D7S82012,13
D13S31712,13
FGA22
TH016,9.3
TPOX8,11
vWA15,18

Run an STR similarity search on this cell line
Publications

PubMed=28561041; DOI=10.1038/ncomms15440; PMCID=PMC5460020
Antje Sucker, Fang Zhao, Natalia Pieper, Christina Heeke, Raffaela Maltaner, Nadine Stadtler, Birgit Real, Nicola Bielefeld, Sebastian Howe, Benjamin Weide, Ralf Gutzmer ...Show all 23 authors... , Jochen Sven Utikal, Carmen Loquai, Helen Gogas, Ludger Klein-Hitpass, Michael Zeschnigk, Astrid Maria Westendorf, Mirko Trilling, Susanne Horn, Bastian Schilling, Dirk Schadendorf, Klaus Georg Griewank, Annette Paschen; Show fewer authors
Acquired IFNgamma resistance impairs anti-tumor immunity and gives rise to T-cell-resistant melanoma lesions.
Nat. Commun. 8:15440.1-15440.15(2017)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C288
ESTDAB; ESTDAB-215
Encyclopedic resources Wikidata; Q54903815
Gene expression databases GEO; GSM2545604
Polymorphism and mutation databases Progenetix; CVCL_C288
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number14