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Cellosaurus WM373 (CVCL_C277)

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Cell line name WM373
Synonyms WM-373; WM 373
Accession CVCL_C277
Resource Identification Initiative To cite this cell line use: WM373 (RRID:CVCL_C277)
Comments Part of: Wistar Institute melanoma cell line collection.
Characteristics: Pigmented.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Back, skin; UBERON=UBERON_0001068.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7156 ! WM75
Sex of cell Male
Age at sampling 49Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133817
D3S135814
D5S81811
D7S8208
D8S117913
D13S31712
D16S53912,13
D18S5114,16
D19S43312,14
D21S1129
FGA20
TH016
TPOX9,11
vWA17

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Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=3856042; DOI=10.1093/jnci/74.2.283
Meenhard Herlyn, Gloria Brady Balaban-Malenbaum, Jeannette L. Bennicelli, DuPont Guerry 4th, Ruth Halaban, Dorothee Herlyn, David E. Elder, Gerd G. Maul, Zenon Steplewski, Peter Carey Nowell, Wallace H. Clark Jr., Hilary Koprowski;
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
J. Natl. Cancer Inst. 74:283-289(1985)

PubMed=4053039
Meenhard Herlyn, Jan Thurin, Gloria Brady Balaban-Malenbaum, Jeannette L. Bennicelli, Dorothee Herlyn, David E. Elder, Edward Bondi, DuPont Guerry 4th, Peter Carey Nowell, Wallace H. Clark Jr., Hilary Koprowski;
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Meenhard Herlyn;
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

Cross-references
Cell line collections (Providers) Rockland; WM373-01-0001
Cell line databases/resources cancercelllines; CVCL_C277
Encyclopedic resources Wikidata; Q54994291
Polymorphism and mutation databases Cosmic; 928687
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number23