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Cellosaurus WM1862 (CVCL_C268)

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Cell line name WM1862
Synonyms WM-1862; WM 1862; EST75
Accession CVCL_C268
Resource Identification Initiative To cite this cell line use: WM1862 (RRID:CVCL_C268)
Comments Part of: Wistar Institute melanoma cell line collection.
Characteristics: Pigmented.
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
HLA typing Source: PubMed=15592718
Class I
HLA-AA*32:01,68:01:02
HLA-BB*14:01
HLA-CC*08:01
Class II
HLA-DPDPB1*04:02,02:01:02
HLA-DQDQB1*02:01
HLA-DRDRB1*07:01
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-075; Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133824,25
D3S135816,18
D5S81811,14
D7S82010
D8S117913,14
D13S3179,11
D16S53913
D18S5112,17
D19S43313,14
D21S1128,29
FGA20,21
TH017,9.3
TPOX8,11
vWA15,17

Run an STR similarity search on this cell line
Web pages Info; Wistar; -; https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966
Teresa Rodriguez, Rosa Mendez, Chrissy H. Roberts, Francisco Ruiz-Cabello Osuna, I. Anthony Dodi, Miguel Angel Lopez-Nevot, Laura Paco, Isabel Maleno, Steven G.E. Marsh, Graham Pawelec, Federico Garrido;
High frequency of homozygosity of the HLA region in melanoma cell lines reveals a pattern compatible with extensive loss of heterozygosity.
Cancer Immunol. Immunother. 54:141-148(2005)

PubMed=17260012; DOI=10.1038/sj.onc.1210252
Goran Jonsson, Christina Dahl, Johan Staaf, Troy Sandberg, Par-Ola Bendahl, Markus Ringner, Per Guldberg, Ake Borg;
Genomic profiling of malignant melanoma using tiling-resolution arrayCGH.
Oncogene 26:4738-4748(2007)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Christina Dahl, Claus Christensen, Goran Jonsson, Anders Lorentzen, Mette Louise Skjodt, Ake Borg, Graham Pawelec, Per Guldberg;
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line collections (Providers) Rockland; WM1862-01-0001
Cell line databases/resources cancercelllines; CVCL_C268
ESTDAB; ESTDAB-075
Encyclopedic resources Wikidata; Q54994200
Gene expression databases GEO; GSM156010
Polymorphism and mutation databases Cosmic; 972270
Cosmic; 1047654
Cosmic; 2163803
IARC_TP53; 26081
Progenetix; CVCL_C268
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number27