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Cellosaurus HS181 (CVCL_C229)

[Text version]
Cell line name HS181
Synonyms KIe001-A
Accession CVCL_C229
Resource Identification Initiative To cite this cell line use: HS181 (RRID:CVCL_C229)
Comments From: Karolinska Institutet; Stockholm; Sweden.
Registration: Swiss research registry; BAG-hES-IMP-0009.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC03-09.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A8HR (HS181 EGFP-2A-SCL)CVCL_A8HS (HS181 EGFP-2A-RUNX1c)CVCL_EG08 (HS181-GFP)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
Publications

PubMed=12832363; DOI=10.1093/humrep/deg290
Outi Hovatta, Milla Mikkola, Karin Gertow, Anne-Marie Stromberg, Jose Inzunza, Julius Hreinsson, Bjorn Rozell, Elisabeth Syk Lundberg, Michael Andang, Lars Ahrlund-Richter;
A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells.
Hum. Reprod. 18:1404-1409(2003)

PubMed=17572666; DOI=10.1038/nbt1318
Oluseun Adewumi, Behrouz Aflatoonian, Lars Ahrlund-Richter, Michal Amit, Peter W. Andrews, Gemma Beighton, Paul A. Bello, Nissim Benvenisty, Lorraine S. Berry, Simon Bevan, Barak Blum ...Show all 85 authors... , Justin Brooking, Kevin G. Chen, Andre B.-H. Choo, Gary A. Churchill, Marie Corbel, Ivan Damjanov, Jonathan S. Draper, Petr Dvorak, Katarina Emanuelsson, Roland A. Fleck, Angela Ford, Karin Gertow, Marina Gertsenstein, Paul J. Gokhale, Rebecca S. Hamilton, Ales Hampl, Lyn E. Healy, Outi Hovatta, Johan Hyllner, Marta P. Imreh, Joseph Itskovitz-Eldor, Jamie Jackson, Jacqueline L. Johnson, Mark Jones, Kehkooi Kee, Benjamin L. King, Barbara B. Knowles, Majlinda Lako, Franck Lebrin, Barbara S. Mallon, Daisy Manning, Yoav Mayshar, Ronald Davies Graham McKay, Anna E. Michalska, Milla Mikkola, Maria Mileikovsky, Stephen Lewis Minger, Harry D. Moore, Christine L. Mummery, Andras Nagy, Norio Nakatsuji, Carmel M. O'Brien, Steve Kah-Weng Oh, Cia Olsson, Timo Otonkoski, Kye-Yoon Park, Robert Passier, Hema Patel, Minal J. Patel, Roger Arnold Pedersen, Martin F. Pera, Marian S. Piekarczyk, Renee A. Reijo Pera, Benjamin E. Reubinoff, Allan J. Robins, Janet Rossant, Peter Rugg-Gunn, Thomas C. Schulz, Henrik Semb, Eric S. Sherrer, Henrike Siemen, Glyn N. Stacey, Miodrag Stojkovic, Hirofumi Suemori, Jin Szatkiewicz, Tikva Tako Turetsky, Timo Tuuri, Stieneke van den Brink, Kristina Vintersten, Sanna Vuoristo, Dorien Ward-van Oostwaard, Thomas A. Weaver, Lesley A. Young, Wei-Dong Zhang; Show fewer authors
International Stem Cell Initiative
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=18930318; DOI=10.1016/j.leukres.2008.08.028
Purificacion Catalina, Clara Bueno, Rosa Montes, Ana Isabel Nieto Ruiz de Zarate, Gertrudis Ligero, Laura Sanchez, Maria Jara-Acevedo, Ana Rasillo, Alberto Orfao, Juan Cruz Cigudosa, Outi Hovatta ...Show all 13 authors... , Melvyn Francis Greaves, Pablo Menendez; Show fewer authors
Genetic stability of human embryonic stem cells: a first-step toward the development of potential hESC-based systems for modeling childhood leukemia.
Leuk. Res. 33:980-990(2009)

PubMed=20198446; DOI=10.1007/s11626-010-9308-0; PMCID=PMC2855803
Susanne Strom, Frida Holm, Rosita Bergstrom, Anne-Marie Stromberg, Outi Hovatta;
Derivation of 30 human embryonic stem cell lines -- improving the quality.
In Vitro Cell. Dev. Biol. Anim. 46:337-344(2010)

PubMed=20641038; DOI=10.1002/stem.471; PMCID=PMC2996086
Ivan Gutierrez-Aranda, Veronica Ramos-Mejia, Clara Bueno, Martin Munoz-Lopez, Pedro J. Real, Angela Macia, Laura Sanchez, Gertrudis Ligero, Jose L. Garcia-Parez, Pablo Menendez;
Human induced pluripotent stem cells develop teratoma more efficiently and faster than human embryonic stem cells regardless the site of injection.
Stem Cells 28:1568-1570(2010)

PubMed=20736931; DOI=10.1038/mt.2010.179; PMCID=PMC2997587
Veronica Ramos-Mejia, Gustavo J. Melen Frajlich, Laura Sanchez, Ivan Gutierrez-Aranda, Gertrudis Ligero, Jose L. Cortes, Pedro J. Real, Clara Bueno, Pablo Menendez;
Nodal/activin signaling predicts human pluripotent stem cell lines prone to differentiate toward the hematopoietic lineage.
Mol. Ther. 18:2173-2181(2010)

PubMed=21217828; DOI=10.1371/journal.pone.0015329; PMCID=PMC3013107
Susanne Strom, Kenny Alexandra Rodriguez-Wallberg, Frida Holm, Rosita Bergstrom, Linda Eklund, Anne-Marie Stromberg, Outi Hovatta;
No relationship between embryo morphology and successful derivation of human embryonic stem cell lines.
PLoS ONE 5:e15329.1-e15329.5(2010)

PubMed=24463987; DOI=10.1038/ncomms4195
Sergey Rodin, Liselotte Antonsson, Colin Niaudet, Oscar E. Simonson, Elina Salmela, Emil M. Hansson, Anna Domogatskaya, Zhi-Jie Xiao, Pauliina Damdimopoulou, Mona Sheikhi, Jose Inzunza ...Show all 22 authors... , Ann-Sofie Nilsson, Duncan E.C. Baker, Raoul Kuiper, Yi Sun, Elisabeth Syk Lundberg, Magnus Nordenskjold, Karl-Henrik Grinnemo, Juha Kere, Christer Betsholtz, Outi Hovatta, Karl Tryggvason; Show fewer authors
Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment.
Nat. Commun. 5:3195.1-3195.13(2014)

PubMed=32339905; DOI=10.1016/j.scr.2020.101810
Heather Main, Mona Hedenskog, Ganesh Acharya, Outi Hovatta, Fredrik Lanner;
Karolinska Institutet Human Embryonic Stem Cell Bank.
Stem Cell Res. 45:101810-101810(2020)

Cross-references
Cell line databases/resources hPSCreg; KIe001-A
SKIP; SKIP001792
Encyclopedic resources Wikidata; Q54896297
Gene expression databases GEO; GSM569193
GEO; GSM569194
GEO; GSM1293456
GEO; GSM1293457
GEO; GSM1293458
GEO; GSM1293459
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number17