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Cellosaurus RD rho-0 (CVCL_C1YP)

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Cell line name RD rho-0
Accession CVCL_C1YP
Resource Identification Initiative To cite this cell line use: RD rho-0 (RRID:CVCL_C1YP)
Comments Population: Caucasian.
Characteristics: Cell line devoid of mitochondrial DNA (rho0). Obtained by growth of parental cell line with ethidium bromide.
Derived from site: In situ; Pelvis, muscle; UBERON=UBERON_0001325.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>T); ClinVar=VCV000373003; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1649 (RD)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=10899454; DOI=10.1016/S0960-8966(00)00096-1
Lodovica Vergani, Alan R. Prescott, Ian James Holt;
Rhabdomyosarcoma rho(0) cells: isolation and characterization of a mitochondrial DNA depleted cell line with 'muscle-like' properties.
Neuromuscul. Disord. 10:454-459(2000)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C1YP
Encyclopedic resources Wikidata; Q114312780
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number6