Cellosaurus logo
expasy logo

Cellosaurus SJ-HGGX39c (CVCL_C1NK)

[Text version]
Cell line name SJ-HGGX39c
Synonyms SJHGG015760_C2
Accession CVCL_C1NK
Resource Identification Initiative To cite this cell line use: SJ-HGGX39c (RRID:CVCL_C1NK)
Comments Characteristics: Derived from a patient-derived xenograft.
Doubling time: 3.7 days (PubMed=34215733).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain, cerebral cortex; UBERON=UBERON_0000956.
Sequence variations
  • Mutation; HGNC; HGNC:20893; BCOR; Simple; p.Gly1429_Thr1431fs (c.4286_4293delCCAGAGCG); Zygosity=Homozygous (PubMed=34215733).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (PubMed=34215733).
  • Mutation; HGNC; HGNC:8803; PDGFRA; Simple; p.Ser1045Phe (c.3134C>T); Zygosity=Heterozygous (PubMed=34215733).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Heterozygous (PubMed=34215733).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 10-11Y
Category Cancer cell line
STR profile Source(s): PubMed=34215733

Markers:
AmelogeninX,Y
CSF1PO12
D3S135812,16
D5S81811
D7S8208,9
D8S117912,14
D13S3178,13
D16S53911,12
D18S5117
D21S1129,30
FGA23,24
Penta D11,12
Penta E7,12
TH018,9
TPOX9,11
vWA14,19

Run an STR similarity search on this cell line
Web pages Provider; PBTP; -; https://pbtp.stjude.cloud/sample-details/29969/baker/SJHGG015760/SJ-HGGX39/Cell%20Line
Publications

PubMed=34215733; DOI=10.1038/s41467-021-24168-8; PMCID=PMC8253809
Chen He, Ke Xu, Xiao-Yan Zhu, Paige S. Dunphy, Brian Gudenas, Wen-Wei Lin, Nathaniel Twarog, Laura D. Hover, Chang-Hyuk Kwon, Lawryn Heath Kasper, Jun-Yuan Zhang ...Show all 40 authors... , Xiao-Yu Li, James Dalton, Barbara Jonchere, Kimberly S. Mercer, Duane G. Currier, William Caufield, Ying-Zhe Wang, Jia Xie, Alberto Broniscer, Cynthia Wetmore, Santhosh A. Upadhyaya, Ibrahim Qaddoumi, Paul Klimo, Frederick A. Boop, Amar Gajjar, Jing-Hui Zhang, Brent A. Orr, Giles W. Robinson, Michelle Monje, Burgess B. Freeman 3rd, Martine Francoise Roussel, Paul A. Northcott, Tao-Sheng Chen, Zoran Rankovic, Gang Wu, Jason Cheng-Hsuan Chiang, Christopher L. Tinkle, Anang A. Shelat, Suzanne J. Baker; Show fewer authors
Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.
Nat. Commun. 12:4089.1-4089.17(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C1NK
Encyclopedic resources Wikidata; Q114313025
Entry history
Entry creation22-Sep-2022
Last entry update10-Apr-2025
Version number7