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Cellosaurus KATO III Ola-R (CVCL_C1ND)

[Text version]
Cell line name KATO III Ola-R
Synonyms KATO-III/olaparib-resistant; Olaparib-resistant KATO-III
Accession CVCL_C1ND
Resource Identification Initiative To cite this cell line use: KATO III Ola-R (RRID:CVCL_C1ND)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_83766; Olaparib.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
Disease Down syndrome (NCIt: C2993)
Gastric signet ring cell adenocarcinoma (NCIt: C5250)
Down syndrome (ORDO: Orphanet_870)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0371 (KATO III)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
Publications

PubMed=32028591; DOI=10.3390/cancers12020334; PMCID=PMC7072281
Jin Won Kim, Ahrum Min, Seock-Ah Im, Hyemin Jang, Yu Jin Kim, Hee-Jun Kim, Kyung-Hun Lee, Tae-Yong Kim, Keun Wook Lee, Do-Youn Oh, Jee-Hyun Kim, Yung-Jue Bang;
TDP1 and TOP1 modulation in olaparib-resistant cancer determines the efficacy of subsequent chemotherapy.
Cancers (Basel) 12:334.1-334.17(2020)

Cross-references
Encyclopedic resources Wikidata; Q114311804
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number5