Cellosaurus cell line TT10603 (CVCL

Cellosaurus TT10603 (CVCL_C1MK)

Cross-references
Cell line name	TT10603
Accession	CVCL_C1MK
Resource Identification Initiative	To cite this cell line use: TT10603 (RRID:CVCL_C1MK)
Comments	Population: Chinese. Doubling time: 67.6 +- 4.2 hours (PubMed=29100338). Derived from site: In situ; Brainstem, pons; UBERON=UBERON_0000988.
Sequence variations	Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Lys28Met (c.83A>T) (H3.3K27M); ClinVar=VCV000376435; Zygosity=Unspecified (PubMed=29100338). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=29100338).
Disease	Diffuse intrinsic pontine glioma (NCIt: C94764) Diffuse intrinsic pontine glioma (ORDO: Orphanet_497188)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	7Y
Category	Cancer cell line
Publications	PubMed=29100338; DOI=10.18632/oncotarget.19656; PMCID=PMC5652732 Cheng Xu, Xiao-Qing Liu, Yi-Bo Geng, Qing-Ran Bai, Chang-Cun Pan, Yu Sun, Xin Chen, Hai Yu, Yu-Liang Wu, Peng Zhang, Wen-Hao Wu ...Show all 23 authors... , Yu Wang, Zhen Wu, Jun-Ting Zhang, Zhao-Hui Wang, Rui Yang, Jenna Lewis, Darell Doty Bigner, Fang-Ping Zhao, Yi-Ping He, Hai Yan, Qin Shen, Li-Wei Zhang; Show fewer authors Patient-derived DIPG cells preserve stem-like characteristics and generate orthotopic tumors. Oncotarget 8:76644-76655(2017)
Cell line databases/resources	cancercelllines; CVCL_C1MK
Encyclopedic resources	Wikidata; Q114313130
Entry history
Entry creation	22-Sep-2022
Last entry update	19-Dec-2024
Version number	6