Cellosaurus logo
expasy logo

Cellosaurus betaG 49/206 (CVCL_C1JY)

[Text version]
Cell line name betaG 49/206
Synonyms betaG49/206; BG 49/206
Accession CVCL_C1JY
Resource Identification Initiative To cite this cell line use: betaG 49/206 (RRID:CVCL_C1JY)
Comments Characteristics: Transfected with a pCB6-INS-Neo, a pCMV8-GK-IRES-GPT and a pCB7-GLUT2-HygroR constructs (PubMed=9166666).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6081; INS.
Genetic integration: Method=Transfection; Gene=RGD; 2670; Gck.
Genetic integration: Method=Transfection; Gene=RGD; 3705; Slc2a2.
Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Rat insulinoma (NCIt: C121566)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS_0000603.
Hierarchy Parent: CVCL_C1JW (betaG 23/21)
Sex of cell Male
Age at sampling 666D
Category Cancer cell line
Publications

PubMed=9166666; DOI=10.2337/diab.46.6.958
Samuel A. Clark, Christian Quaade, Heba Constandy, Pernille Hansen, Philippe Alexandre Halban, Sarah Ferber, Christopher Bang Newgard, Karl Normington;
Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression.
Diabetes 46:958-967(1997)

PubMed=9166667; DOI=10.2337/diab.46.6.968
Hans-Ewald Hohmeier, Hector BeltrandelRio, Samuel A. Clark, Rosemarie Henkel-Rieger, Karl Normington, Christopher Bang Newgard;
Regulation of insulin secretion from novel engineered insulinoma cell lines.
Diabetes 46:968-977(1997)

Cross-references
Encyclopedic resources Wikidata; Q114310745
Entry history
Entry creation22-Sep-2022
Last entry update14-Aug-2025
Version number9