Cellosaurus cell line TAT2SF T4 (CVCL

Cellosaurus TAT2SF T4 (CVCL_C1HK)

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Cell line name

TAT2SF T4

Synonyms

Accession

CVCL_C1HK

Resource Identification Initiative

To cite this cell line use: TAT2SF T4 (RRID:CVCL_C1HK)

Comments

Characteristics: Transfected with a pSXneo-1.6-T2AG3 plasmid that contains 1.6 kb of telomeric repeat sequences (PubMed=9357546).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.

Sequence variations

Mutation; HGNC; HGNC:795; ATM; Simple; p.Phe1774Lysfs*17 (c.5320_5326del) (c.5320del7); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:795; ATM; Simple; p.Trp2769Ter (c.8307G>A); ClinVar=VCV000189104; Zygosity=Heterozygous (from parent cell line).

Disease

Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_F611 (TAT2SF)
Children:

CVCL_C1HM (TAT2SF T4-F)

Sex of cell

Female