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Cellosaurus HEK 293T-hACE2 (CVCL_C1G1)

[Text version]
Cell line name HEK 293T-hACE2
Accession CVCL_C1G1
Resource Identification Initiative To cite this cell line use: HEK 293T-hACE2 (RRID:CVCL_C1G1)
Comments Group: SARS-CoV-2 research cell line.
Characteristics: Transduced with a pHIV-CMV-hACE2-IRES-PuroR construct.
Transfected with: HGNC; 13557; ACE2.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA].
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=35757815; DOI=10.1016/j.crmeth.2022.100252
Ssenyange G., Kerfoot M., Zhao M., Farhadian S., Chen S.-D., Peng L., Ren P., Dela Cruz C.S., Gupta S., Sutton R.E.
Development of an efficient reproducible cell-cell transmission assay for rapid quantification of SARS-CoV-2 spike interaction with hACE2.
Cell Rep. Methods 2:100252.1-100252.19(2022)

Cross-references
Encyclopedic resources Wikidata; Q114311577
Entry history
Entry creation22-Sep-2022
Last entry update05-Oct-2023
Version number5