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Cellosaurus BL-72 (CVCL_C157)

[Text version]
Cell line name BL-72
Synonyms BL72; BL 72; BL 072; IARC/BL72; IARC/BL 72; IARC-BL72; IARC BL72; IARC BL 72
Accession CVCL_C157
Resource Identification Initiative To cite this cell line use: BL-72 (RRID:CVCL_C157)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Algerian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 7553; MYC; Simple; p.Thr73Ile (c.218C>T); ClinVar=VCV000376300; Zygosity=Unspecified (PubMed=8108117).
HLA typing Source: PubMed=3037521
Class I
HLA-AA*11,28
HLA-BB*27,45
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_IV24 ! IARC-307
Sex of cell Male
Age at sampling 11Y
Category Cancer cell line
Publications

PubMed=6592381; DOI=10.1093/jnci/73.4.841
Favrot M.-C., Philip I., Philip T., Portoukalian J., Dore J.-F., Lenoir G.M.
Distinct reactivity of Burkitt's lymphoma cell lines with eight monoclonal antibodies correlated with the ethnic origin.
J. Natl. Cancer Inst. 73:841-847(1984)

PubMed=2985508; DOI=10.1002/ijc.2910350404
Rowe M., Rooney C.M., Rickinson A.B., Lenoir G.M., Rupani H., Moss D.J., Stein H., Epstein M.A.
Distinctions between endemic and sporadic forms of Epstein-Barr virus-positive Burkitt's lymphoma.
Int. J. Cancer 35:435-441(1985)

PubMed=3905596
Favrot M.-C., Philip I., Philip T., Cabrillat H., Pinatel C., Dore J.-F., Lenoir G.M.
Immunophenotypic classification of 28 Burkitt cell lines with monoclonal antibodies and reagent selection for bone-marrow purging.
IARC Sci. Publ. 60:447-452(1985)

PubMed=3934070
Lenoir G.M., Vuillaume M., Bonnardel C.
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=3037521; DOI=10.1073/pnas.84.13.4567
Masucci M.G., Torsteinsdottir S., Colombani J., Brautbar C., Klein E., Klein G.
Down-regulation of class I HLA antigens and of the Epstein-Barr virus-encoded latent membrane protein in Burkitt lymphoma lines.
Proc. Natl. Acad. Sci. U.S.A. 84:4567-4571(1987)

PubMed=8108117
Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Klangby U., Okan I., Magnusson K.P., Wendland M., Lind P., Wiman K.G.
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=11793449; DOI=10.1002/gcc.10022
Sobol H., Benziane A., Kerangueven F., Yin L., Noguchi T., Pauly S., Eisinger F., Longy M., Romeo G., Lenoir G.M., Birnbaum D.
Genome-wide search for loss of heterozygosity in Burkitt lymphoma cell lines.
Genes Chromosomes Cancer 33:217-224(2002)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C157
Encyclopedic resources Wikidata; Q54797246
Polymorphism and mutation databases Cosmic; 931114
Cosmic; 2804860
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number16