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Cellosaurus BL-67 (CVCL_C156)

[Text version]
Cell line name BL-67
Synonyms BL67; BL 67; BL 067; IARC/BL67; IARC/BL 67; IARC-BL67; IARC BL67; IARC BL 67
Accession CVCL_C156
Resource Identification Initiative To cite this cell line use: BL-67 (RRID:CVCL_C156)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Caucasian.
Doubling time: ~10-25 hours (DSMZ=ACC-921).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 7553; MYC; Simple; p.Pro75Ser (c.223C>T); Zygosity=Unspecified (PubMed=8108117).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A1DZ ! BL-78
CVCL_IV27 ! IARC-309
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line
Publications

PubMed=3004968; DOI=10.1002/j.1460-2075.1985.tb04140.x
Eick D., Piechaczyk M., Henglein B., Blanchard J.-M., Traub B., Kofler E., Wiest S., Lenoir G.M., Bornkamm G.-W.
Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.
EMBO J. 4:3717-3725(1985)

PubMed=3934070
Lenoir G.M., Vuillaume M., Bonnardel C.
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=1620543
Apel T.W., Mautner J., Polack A., Bornkamm G.-W., Eick D.
Two antisense promoters in the immunoglobulin mu-switch region drive expression of c-myc in the Burkitt's lymphoma cell line BL67.
Oncogene 7:1267-1271(1992)

PubMed=8108117
Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Klangby U., Okan I., Magnusson K.P., Wendland M., Lind P., Wiman K.G.
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=11793449; DOI=10.1002/gcc.10022
Sobol H., Benziane A., Kerangueven F., Yin L., Noguchi T., Pauly S., Eisinger F., Longy M., Romeo G., Lenoir G.M., Birnbaum D.
Genome-wide search for loss of heterozygosity in Burkitt lymphoma cell lines.
Genes Chromosomes Cancer 33:217-224(2002)

PubMed=18647998; DOI=10.1093/jncimonographs/lgn011
Dib A., Gabrea A., Glebov O.K., Bergsagel P.L., Kuehl W.M.
Characterization of MYC translocations in multiple myeloma cell lines.
J. Natl. Cancer Inst. Monogr. 39:25-31(2008)

Cross-references
Cell line collections (Providers) DSMZ; ACC-921
Cell line databases/resources DSMZCellDive; ACC-921
Encyclopedic resources Wikidata; Q54797238
Polymorphism and mutation databases Cosmic; 931122
Cosmic; 2804862
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number18