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Cellosaurus BL-67 (CVCL_C156)

[Text version]
Cell line name BL-67
Synonyms BL67; BL 67; BL 067; IARC/BL67; IARC/BL 67; IARC-BL67; IARC BL67; IARC BL 67
Accession CVCL_C156
Resource Identification Initiative To cite this cell line use: BL-67 (RRID:CVCL_C156)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Caucasian.
Doubling time: ~10-25 hours (DSMZ=ACC-921).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:7553; MYC; Simple; p.Pro75Ser (c.223C>T); Zygosity=Unspecified (PubMed=8108117).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_A1DZ ! BL-78
CVCL_IV27 ! IARC-309
Sex of cell Female
Age at sampling 35Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-921

Markers:
AmelogeninX
CSF1PO10,12
D2S133817,23
D3S135814,16
D5S81811,13
D7S82010,12
D8S117912,13
D13S31710,12
D16S53911
D18S5112,20
D19S43312,16
D21S1127,28
FGA21,23
Penta D9,13
Penta E7,11
TH016,9.3
TPOX8
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=3004968; DOI=10.1002/j.1460-2075.1985.tb04140.x; PMCID=PMC554723
Dirk Eick, Marc Piechaczyk, Berthold Henglein, Jean-Marie Blanchard, Brigitte Traub, Edith Kofler, Sieglinde Wiest, Gilbert Marcel Lenoir, Georg-Wilhelm Bornkamm;
Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.
EMBO J. 4:3717-3725(1985)

PubMed=3934070
Gilbert Marcel Lenoir, Michele Vuillaume, Colette Bonnardel;
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=1620543
Thomas W. Apel, Josef Mautner, Axel Polack, Georg-Wilhelm Bornkamm, Dirk Eick;
Two antisense promoters in the immunoglobulin mu-switch region drive expression of c-myc in the Burkitt's lymphoma cell line BL67.
Oncogene 7:1267-1271(1992)

PubMed=8108117
Thomas Albert, Birgit Urlbauer, Franz Kohlhuber, Bettina Hammersen, Dirk Eick;
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Ulf Klangby, Ismail Okan, Kristinn Petur Magnusson, Martin Wendland, Peter Lind, Klas G. Wiman;
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=11793449; DOI=10.1002/gcc.10022
Hagay Sobol, Athmane Benziane, Fabienne Kerangueven, Luo Yin, Tetsuro Noguchi, Suzanne Pauly, Francois Eisinger, Michel Longy, Giovanni Romeo, Gilbert Marcel Lenoir, Daniel Birnbaum;
Genome-wide search for loss of heterozygosity in Burkitt lymphoma cell lines.
Genes Chromosomes Cancer 33:217-224(2002)

PubMed=18647998; DOI=10.1093/jncimonographs/lgn011; PMCID=PMC2737184
Amel Dib, Ana Gabrea, Oleg K. Glebov, Peter Leif Bergsagel, Walter Michael Kuehl;
Characterization of MYC translocations in multiple myeloma cell lines.
J. Natl. Cancer Inst. Monogr. 39:25-31(2008)

Cross-references
Cell line collections (Providers) DSMZ; ACC-921
Cell line databases/resources DSMZCellDive; ACC-921
Encyclopedic resources Wikidata; Q54797238
Polymorphism and mutation databases Cosmic; 931122
Cosmic; 2804862
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number20