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Cellosaurus BL-49 (CVCL_C150)

[Text version]
Cell line name BL-49
Synonyms BL49; BL 49; BL 049; IARC/BL49; IARC/BL 49; IARC-BL49; IARC BL49; IARC-BL-49; IARC BL 49
Accession CVCL_C150
Resource Identification Initiative To cite this cell line use: BL-49 (RRID:CVCL_C150)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Caucasian.
Virology: EBV-negative.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_IV15 ! BL-50
CVCL_VQ26 ! IARC-208
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Publications

PubMed=6090749; DOI=10.1093/jnci/73.4.835
Irene Philip, Thierry Philip, Marie-Christine Favrot, Michele Vuillaume, Bernard Fontaniere, Didier Chamard, Gilbert Marcel Lenoir;
Establishment of lymphomatous cell lines from bone marrow samples from patients with Burkitt's lymphoma.
J. Natl. Cancer Inst. 73:835-840(1984)

PubMed=6592381; DOI=10.1093/jnci/73.4.841
Marie-Christine Favrot, Irene Philip, Thierry Philip, Jacques Portoukalian, Jean-Francois Dore, Gilbert Marcel Lenoir;
Distinct reactivity of Burkitt's lymphoma cell lines with eight monoclonal antibodies correlated with the ethnic origin.
J. Natl. Cancer Inst. 73:841-847(1984)

PubMed=3905596
Marie-Christine Favrot, Irene Philip, Thierry Philip, Helene Cabrillat, Christiane Pinatel, Jean-Francois Dore, Gilbert Marcel Lenoir;
Immunophenotypic classification of 28 Burkitt cell lines with monoclonal antibodies and reagent selection for bone-marrow purging.
IARC Sci. Publ. 60:447-452(1985)

PubMed=3934070
Gilbert Marcel Lenoir, Michele Vuillaume, Colette Bonnardel;
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=3026973; DOI=10.1002/ijc.2910390215
Barbro Ehlin-Henriksson, Agneta Manneborg-Sandlund, George Klein;
Expression of B-cell-specific markers in different Burkitt lymphoma subgroups.
Int. J. Cancer 39:211-218(1987)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Jacques H.M. Cohen, Jean-Pierre Revillard, Jean-Pierre Magaud, Gilbert Marcel Lenoir, Michele Vuillaume, Anne-Marie Manel, Claude Vincent, Paul-Andre Bryon;
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

PubMed=2052620; DOI=10.1073/pnas.88.12.5413; PMCID=PMC51883
Gianluca Gaidano, Paola Ballerini, Jerry Z. Gong, Giorgio Inghirami, Antonino Neri, Elizabeth W. Newcomb, Ian Trevor Magrath, Daniel M. Knowles, Riccardo Dalla-Favera;
p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.
Proc. Natl. Acad. Sci. U.S.A. 88:5413-5417(1991)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Ulf Klangby, Ismail Okan, Kristinn Petur Magnusson, Martin Wendland, Peter Lind, Klas G. Wiman;
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=11793449; DOI=10.1002/gcc.10022
Hagay Sobol, Athmane Benziane, Fabienne Kerangueven, Luo Yin, Tetsuro Noguchi, Suzanne Pauly, Francois Eisinger, Michel Longy, Giovanni Romeo, Gilbert Marcel Lenoir, Daniel Birnbaum;
Genome-wide search for loss of heterozygosity in Burkitt lymphoma cell lines.
Genes Chromosomes Cancer 33:217-224(2002)

PubMed=24590883; DOI=10.1002/gcc.22161
Eva-Maria Murga Penas, Georgia Schilling, Petra Behrmann, Marianne Klokow, Eik Vettorazzi, Carsten Bokemeyer, Judith Dierlamm;
Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.
Genes Chromosomes Cancer 53:497-515(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C150
Encyclopedic resources Wikidata; Q54797208
Polymorphism and mutation databases Cosmic; 931120
IARC_TP53; 139
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number21