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Cellosaurus BL-36 (CVCL_C146)

[Text version]
Cell line name BL-36
Synonyms BL36; BL 36; BL 036; IARC/BL36; IARC/BL 36; IARC-BL36; IARC BL36; IARC BL 36
Accession CVCL_C146
Resource Identification Initiative To cite this cell line use: BL-36 (RRID:CVCL_C146)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Algerian.
Virology: Contains a complete EBV genome (strain BL36) which has been sequenced (PubMed=25787276). Contains from 5 to 10 episomal copies of EBV (PubMed=8382295).
Doubling time: ~24 hours (DSMZ=ACC-917).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Bone, jaw; UBERON=UBERON_0001708.
Cell type: B-cell; CL=CL_0000236.
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_M641 ! BL-42
CVCL_M565 ! BL-43
CVCL_M566 ! BL-44
CVCL_IV23 ! IARC-174
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-917

Markers:
AmelogeninX
CSF1PO10,11
D2S133817,23
D3S135815,18
D5S8189,11
D7S82011,12
D8S117912,14
D13S3178,13
D16S53911,12
D18S5115
D19S43314
D21S1129.2,33.2
FGA21,22
Penta D3,11
Penta E13,17
TH017,9
TPOX8
vWA17

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Publications

PubMed=6231253; DOI=10.1002/ijc.2910330407
Barbro Ehlin-Henriksson, George Klein;
Distinction between Burkitt lymphoma subgroups by monoclonal antibodies: relationships between antigen expression and type of chromosomal translocation.
Int. J. Cancer 33:459-463(1984)

PubMed=6592381; DOI=10.1093/jnci/73.4.841
Marie-Christine Favrot, Irene Philip, Thierry Philip, Jacques Portoukalian, Jean-Francois Dore, Gilbert Marcel Lenoir;
Distinct reactivity of Burkitt's lymphoma cell lines with eight monoclonal antibodies correlated with the ethnic origin.
J. Natl. Cancer Inst. 73:841-847(1984)

PubMed=2985508; DOI=10.1002/ijc.2910350404
Martin Rowe, Cliona M. Rooney, Alan Bernard Rickinson, Gilbert Marcel Lenoir, Hitesh Rupani, Denis J. Moss, Harald Stein, Michael Anthony Epstein;
Distinctions between endemic and sporadic forms of Epstein-Barr virus-positive Burkitt's lymphoma.
Int. J. Cancer 35:435-441(1985)

PubMed=3905596
Marie-Christine Favrot, Irene Philip, Thierry Philip, Helene Cabrillat, Christiane Pinatel, Jean-Francois Dore, Gilbert Marcel Lenoir;
Immunophenotypic classification of 28 Burkitt cell lines with monoclonal antibodies and reagent selection for bone-marrow purging.
IARC Sci. Publ. 60:447-452(1985)

PubMed=3934070
Gilbert Marcel Lenoir, Michele Vuillaume, Colette Bonnardel;
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Jacques H.M. Cohen, Jean-Pierre Revillard, Jean-Pierre Magaud, Gilbert Marcel Lenoir, Michele Vuillaume, Anne-Marie Manel, Claude Vincent, Paul-Andre Bryon;
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677
Christopher D. Gregory, Ruth J. Murray, Carole F. Edwards, Alan Bernard Rickinson;
Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.
J. Exp. Med. 167:1811-1824(1988)

PubMed=8382295; DOI=10.1128/JVI.67.3.1292-1299.1993; PMCID=PMC237496
Henri-Jacques Delecluse, Sabine Bartnitzke, Wolfgang Hammerschmidt, Jorn Bullerdiek, Georg-Wilhelm Bornkamm;
Episomal and integrated copies of Epstein-Barr virus coexist in Burkitt lymphoma cell lines.
J. Virol. 67:1292-1299(1993)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Ulf Klangby, Ismail Okan, Kristinn Petur Magnusson, Martin Wendland, Peter Lind, Klas G. Wiman;
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=11983026; DOI=10.1186/1475-2867-1-2; PMCID=PMC101226
Florence Poirier, Philippe Bourin, Dominique Bladier, Raymonde Joubert-Caron, Michel Caron;
Effect of 5-azacytidine and galectin-1 on growth and differentiation of the human B lymphoma cell line BL36.
Cancer Cell Int. 1:2.1-2.12(2001)

PubMed=11793449; DOI=10.1002/gcc.10022
Hagay Sobol, Athmane Benziane, Fabienne Kerangueven, Luo Yin, Tetsuro Noguchi, Suzanne Pauly, Francois Eisinger, Michel Longy, Giovanni Romeo, Gilbert Marcel Lenoir, Daniel Birnbaum;
Genome-wide search for loss of heterozygosity in Burkitt lymphoma cell lines.
Genes Chromosomes Cancer 33:217-224(2002)

PubMed=25787276; DOI=10.1128/JVI.03614-14; PMCID=PMC4442510
Anne L. Palser, Nicholas Edwin Grayson, Robert E. White, Craig Corton, Samantha Correia, Mohammed M. Ba Abdullah, Simon J. Watson, Matthew Cotten, John R. Arrand, Paul G. Murray, Martin John Allday ...Show all 15 authors... , Alan Bernard Rickinson, Lawrence S. Young, Paul J. Farrell, Paul Kellam; Show fewer authors
Genome diversity of Epstein-Barr virus from multiple tumor types and normal infection.
J. Virol. 89:5222-5237(2015)

Cross-references
Cell line collections (Providers) DSMZ; ACC-917
Cell line databases/resources DSMZCellDive; ACC-917
Encyclopedic resources Wikidata; Q54797147
Polymorphism and mutation databases Cosmic; 931098
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number19