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Cellosaurus BL-18 (CVCL_C139)

[Text version]
Cell line name BL-18
Synonyms BL18; BL 18; IARC/BL18; IARC/BL 18; IARC-BL18; IARC BL18; IARC-BL-18; IARC BL 18; GM08687; GM17384
Accession CVCL_C139
Resource Identification Initiative To cite this cell line use: BL-18 (RRID:CVCL_C139)
Comments Part of: Human variation panel.
From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: Algerian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:7553; MYC; Simple; p.Thr73Ala (c.217A>G); Zygosity=Unspecified (PubMed=8108117).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VQ19 ! IARC-099
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Publications

PubMed=6825067; DOI=10.1016/0165-4608(83)90138-3
Alain Bernheim, Roland Berger, Gilbert Marcel Lenoir;
Cytogenetic studies on Burkitt's lymphoma cell lines.
Cancer Genet. Cytogenet. 8:223-229(1983)

PubMed=6231253; DOI=10.1002/ijc.2910330407
Barbro Ehlin-Henriksson, George Klein;
Distinction between Burkitt lymphoma subgroups by monoclonal antibodies: relationships between antigen expression and type of chromosomal translocation.
Int. J. Cancer 33:459-463(1984)

PubMed=2985508; DOI=10.1002/ijc.2910350404
Martin Rowe, Cliona M. Rooney, Alan Bernard Rickinson, Gilbert Marcel Lenoir, Hitesh Rupani, Denis J. Moss, Harald Stein, Michael Anthony Epstein;
Distinctions between endemic and sporadic forms of Epstein-Barr virus-positive Burkitt's lymphoma.
Int. J. Cancer 35:435-441(1985)

PubMed=3004968; DOI=10.1002/j.1460-2075.1985.tb04140.x; PMCID=PMC554723
Dirk Eick, Marc Piechaczyk, Berthold Henglein, Jean-Marie Blanchard, Brigitte Traub, Edith Kofler, Sieglinde Wiest, Gilbert Marcel Lenoir, Georg-Wilhelm Bornkamm;
Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.
EMBO J. 4:3717-3725(1985)

PubMed=3934070
Gilbert Marcel Lenoir, Michele Vuillaume, Colette Bonnardel;
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=3026973; DOI=10.1002/ijc.2910390215
Barbro Ehlin-Henriksson, Agneta Manneborg-Sandlund, George Klein;
Expression of B-cell-specific markers in different Burkitt lymphoma subgroups.
Int. J. Cancer 39:211-218(1987)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Jacques H.M. Cohen, Jean-Pierre Revillard, Jean-Pierre Magaud, Gilbert Marcel Lenoir, Michele Vuillaume, Anne-Marie Manel, Claude Vincent, Paul-Andre Bryon;
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677
Christopher D. Gregory, Ruth J. Murray, Carole F. Edwards, Alan Bernard Rickinson;
Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.
J. Exp. Med. 167:1811-1824(1988)

CLPUB00447
Richard A. Mulivor, Sharon F. Suchy;
1992/1993 catalog of cell lines. NIGMS human genetic mutant cell repository. 16th edition. October 1992.
(In misc. document) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda; USA (1992)

PubMed=8108117
Thomas Albert, Birgit Urlbauer, Franz Kohlhuber, Bettina Hammersen, Dirk Eick;
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

PubMed=9473234; DOI=10.1182/blood.V91.5.1680
Ulf Klangby, Ismail Okan, Kristinn Petur Magnusson, Martin Wendland, Peter Lind, Klas G. Wiman;
p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma.
Blood 91:1680-1687(1998)

PubMed=24590883; DOI=10.1002/gcc.22161
Eva-Maria Murga Penas, Georgia Schilling, Petra Behrmann, Marianne Klokow, Eik Vettorazzi, Carsten Bokemeyer, Judith Dierlamm;
Comprehensive cytogenetic and molecular cytogenetic analysis of 44 Burkitt lymphoma cell lines: secondary chromosomal changes characterization, karyotypic evolution, and comparison with primary samples.
Genes Chromosomes Cancer 53:497-515(2014)

Cross-references
Cell line collections (Providers) Coriell; GM08687
Coriell; GM17384
Cell line databases/resources CLO; CLO_0010612
CLO; CLO_0012171
Biological sample resources BioSample; SAMN00798134
Encyclopedic resources Wikidata; Q54797119
Polymorphism and mutation databases Cosmic; 931096
Cosmic; 2804859
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number19