Cellosaurus logo
expasy logo

Cellosaurus SKH1 [Human leukemia] (CVCL_C124)

[Text version]
Cell line name SKH1 [Human leukemia]
Synonyms SKH-1
Accession CVCL_C124
Resource Identification Initiative To cite this cell line use: SKH1 [Human leukemia] (RRID:CVCL_C124)
Comments Population: Japanese.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (PubMed=8313895; PubMed=10576511).
Disease Chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C3174)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8313895; DOI=10.1002/j.1460-2075.1994.tb06288.x; PMCID=PMC394839
Kinuko Mitani, Seishi Ogawa, Tomoyuki U. Tanaka, Hiroyuki Miyoshi, Mineo Kurokawa, Hiroyuki Mano, Yoshio Yazaki, Misao Ohki, Hisamaru Hirai;
Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.
EMBO J. 13:504-510(1994)

PubMed=9510473; DOI=10.1111/j.1349-7006.1998.tb00476.x; PMCID=PMC5921588
Noriko Hosoya, Akira Hangaishi, Seishi Ogawa, Kiyoshi Miyagawa, Kinuko Mitani, Yoshio Yazaki, Hisamaru Hirai;
Frameshift mutations of the hMSH6 gene in human leukemia cell lines.
Jpn. J. Cancer Res. 89:33-39(1998)

PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9
Cord C. Uphoff, Silke Habig, Severine Fombonne, Yoshinobu Matsuo, Hans Gunther Drexler;
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.
Leuk. Res. 23:1055-1060(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=15156182; DOI=10.1038/sj.onc.1207777
Kinuko Mitani;
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
Oncogene 23:4263-4269(2004)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Hilmar Quentmeier, Roderick A.F. MacLeod, Margarete Zaborski, Hans Gunther Drexler;
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

Cross-references
Encyclopedic resources Wikidata; Q54954739
Polymorphism and mutation databases Cosmic; 919117
Cosmic; 947370
Cosmic; 1012118
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number14