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Cellosaurus MOLM-13/DAC (CVCL_C0WK)

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Cell line name MOLM-13/DAC
Accession CVCL_C0WK
Resource Identification Initiative To cite this cell line use: MOLM-13/DAC (RRID:CVCL_C0WK)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_50131; 5-aza-2'-deoxycytidine (Decitabine).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:7132; KMT2A + HGNC; HGNC:7136; MLLT3; Name(s)=KMT2A-MLLT3, MLL-MLLT3, MLL-AF9 (from parent cell line).
  • Mutation; HGNC; HGNC:3765; FLT3; Unexplicit; Internal tandem duplication (FLT3-ITD); ClinVar=VCV000016270; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute monocytic leukemia (NCIt: C8263)
Myelodysplastic syndrome (NCIt: C3247)
Acute monoblastic/monocytic leukemia (ORDO: Orphanet_514)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2119 (MOLM-13)
Sex of cell Male
Age at sampling 20Y
Category Cancer cell line
Publications

PubMed=33669837; DOI=10.3390/ijms22042076; PMCID=PMC7923013
Lubos Janotka, Lucia Messingerova, Kristina Simonicova, Helena Kavcova, Katarina Elefantova, Zdena Sulova, Albert Breier;
Changes in apoptotic pathways in MOLM-13 cell lines after induction of resistance to hypomethylating agents.
Int. J. Mol. Sci. 22:2076.1-2076.24(2021)

Cross-references
Encyclopedic resources Wikidata; Q114312312
Entry history
Entry creation22-Sep-2022
Last entry update27-Nov-2025
Version number7