Cellosaurus cell line GWH04 (CVCL

Cellosaurus GWH04 (CVCL_C0W3)

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Cell line name

GWH04

Synonyms

GWH 04; Fu

Accession

CVCL_C0W3

Resource Identification Initiative

To cite this cell line use: GWH04 (RRID:CVCL_C0W3)

Comments

Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C202163.
Population: Chinese.
Derived from site: In situ; Brain, right temporal lobe; UBERON=UBERON_0002809.

Sequence variations

Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Glu1038Gly (c.3113A>G); ClinVar=VCV000041815; Zygosity=Unspecified (PubMed=36169178).
Mutation; HGNC; HGNC:3430; ERBB2; Simple; p.Ser423Gly (c.1267A>G); ClinVar=VCV001398791; Zygosity=Unspecified (PubMed=36169178).
Mutation; HGNC; HGNC:7127; MLH1; Simple; p.Val384Asp (c.1151T>A); ClinVar=VCV000041632; Zygosity=Unspecified (PubMed=36169178).
Mutation; HGNC; HGNC:7765; NF1; Simple; p.Ter640Argext (c.1918T>C); Zygosity=Unspecified (PubMed=36169178).
Mutation; HGNC; HGNC:8803; PDGFRA; Simple; p.Ser478Pro (c.1432T>C); ClinVar=VCV000041794; Zygosity=Unspecified (PubMed=36169178).
Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Tyr315Ter (c.945T>A); ClinVar=VCV000234509; Zygosity=Unspecified (PubMed=36169178).
Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=36169178).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr205Cys (c.614A>G); ClinVar=VCV000376681; Zygosity=Unspecified (PubMed=36169178).

Disease

Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

72Y

Category

Cancer cell line

STR profile

Source(s): PubMed=36169178

Markers:

Amelogenin	X
CSF1PO	12
D1S1656	15
D2S1338	24
D3S1358	15,16
D5S818	12,13
D6S1043	11,19
D7S820	11,12
D8S1179	12,13
D12S391	22,23
D13S317	9
D16S539	10,12
D19S433	14
D21S11	30
FGA	22,23
Penta D	9,15
Penta E	12,18
TH01	7,9
TPOX	8,9
vWA	14,17

Web pages

Provider; BRICS; BRICS0010; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3825

Publications

PubMed=36169178; DOI=10.3892/ijo.2022.5429; PMCID=PMC9529431
Fang-Ling Cheng, Xue-Yan Wan, Bo-Feng Wang, You-Wei Li, Peng Peng, San-Peng Xu, Chao Han, Feng Mao, Dong-Sheng Guo;
Establishment and characteristics of GWH04, a new primary human glioblastoma cell line.
Int. J. Oncol. 61:139.1-139.14(2022)

Patent=CN114214281B
Fang-Ling Cheng, Xue-Yan Wan, Feng Mao, Bo-Feng Wang, Dong-Sheng Guo;
Human glioblastoma cell line GWH04 and culture method and application thereof.
Patent number CN114214281B, 17-Nov-2023

Cross-references

Cell line databases/resources

cancercelllines; CVCL_C0W3
CCRID; 4201PAT-CCTCC01832

Encyclopedic resources

Wikidata; Q114311552

Entry history

Entry creation

22-Sep-2022

Last entry update

10-Apr-2025

Version number