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Cellosaurus HP-mock (puro) (CVCL_C0UQ)

[Text version]
Cell line name HP-mock (puro)
Synonyms HP-mock
Accession CVCL_C0UQ
Resource Identification Initiative To cite this cell line use: HP-mock (puro) (RRID:CVCL_C0UQ)
Comments Population: Caucasian.
Characteristics: Control cell line for many anti-HPA antibodies cell lines.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=19389219; DOI=10.1111/j.1537-2995.2008.02000.x
Tomoya Hayashi, Kazuta Yasui, Nobuki Matsuyama, Rika Ann Furuta, Yuji Hori, Shigenori Tanaka, Fumiya Hirayama, Yoshihiko Tani, Hirotoshi Shibata, Masayasu Inoue;
Establishment of a novel method for detecting Nak antibodies by using a panel cell line.
Transfusion 49:390-392(2009)

PubMed=20812998; DOI=10.1111/j.1365-2141.2010.08369.x
Tomoya Hayashi, Etsuko Amakishi, Nobuki Matsuyama, Kazuta Yasui, Rika Ann Furuta, Yuji Hori, Yasuo Fukumori, Shigenori Tanaka, Brian R. Curtis, Masayasu Inoue, Fumiya Hirayama;
Detection of antibodies against human platelet antigens 15a and 15b by using a cell line panel.
Br. J. Haematol. 151:402-404(2010)

PubMed=23245717; DOI=10.2450/2012.0126-12; PMCID=PMC3934277
Tomoya Hayashi, Etsuko Amakishi, Nobuki Matsuyama, Kazuta Yasui, Rika Ann Furuta, Yuji Hori, Shigenori Tanaka, Yasuo Fukumori, Fumiya Hirayama;
Detection of anti-human platelet antibodies against integrin alpha2beta1 using cell lines.
Blood Transfus. 12 Suppl. 1:s273-s280(2014)

PubMed=24387678; DOI=10.1111/vox.12118
Etsuko Amakishi, Tomoya Hayashi, Youngil Koh, Nobuki Matsuyama, Hiroyuki Ishii, Harumichi Matsukura, Kazuta Yasui, Fumiya Hirayama;
A new transfectant panel cell line-based MoAb-independent antigen capture assay system for detection of CD36 antibody.
Vox Sang. 106:368-371(2014)

Cross-references
Encyclopedic resources Wikidata; Q112929738
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number9