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Cellosaurus HP-Nak (CVCL_C0UP)

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Cell line name HP-Nak
Synonyms HP-CD36
Accession CVCL_C0UP
Resource Identification Initiative To cite this cell line use: HP-Nak (RRID:CVCL_C0UP)
Comments Population: Caucasian.
Biotechnology: Used in assay systems for the detection of CD36 antibodies (PubMed=19389219; PubMed=24387678).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1663; CD36.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=19389219; DOI=10.1111/j.1537-2995.2008.02000.x
Tomoya Hayashi, Kazuta Yasui, Nobuki Matsuyama, Rika Ann Furuta, Yuji Hori, Shigenori Tanaka, Fumiya Hirayama, Yoshihiko Tani, Hirotoshi Shibata, Masayasu Inoue;
Establishment of a novel method for detecting Nak antibodies by using a panel cell line.
Transfusion 49:390-392(2009)

PubMed=24387678; DOI=10.1111/vox.12118
Etsuko Amakishi, Tomoya Hayashi, Youngil Koh, Nobuki Matsuyama, Hiroyuki Ishii, Harumichi Matsukura, Kazuta Yasui, Fumiya Hirayama;
A new transfectant panel cell line-based MoAb-independent antigen capture assay system for detection of CD36 antibody.
Vox Sang. 106:368-371(2014)

Cross-references
Encyclopedic resources Wikidata; Q112929737
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number9