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Cellosaurus SH-SY5Y-FLAG-NGB (CVCL_C0U0)

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Cell line name SH-SY5Y-FLAG-NGB
Accession CVCL_C0U0
Resource Identification Initiative To cite this cell line use: SH-SY5Y-FLAG-NGB (RRID:CVCL_C0U0)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:14077; NGB (Note=With a C-terminal 3xFLAG tag).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Omics: Proteomics; Quantitative.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; HGNC:427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0019 (SH-SY5Y)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line
Publications

PubMed=34943907; DOI=10.3390/cells10123394; PMCID=PMC8699457
Valeria Manganelli, Illari Salvatori, Michele Costanzo, Antonella Capozzi, Daniela Caissutti, Marianna Caterino, Cristiana Valle, Alberto Ferri, Maurizio Sorice, Margherita Ruoppolo, Tina Garofalo, Roberta Misasi;
Overexpression of neuroglobin promotes energy metabolism and autophagy induction in human neuroblastoma SH-SY5Y cells.
Cells 10:3394.1-3394.18(2021)

PubMed=35128003; DOI=10.1016/j.dib.2022.107843; PMCID=PMC8800053
Michele Costanzo, Marianna Caterino, Illari Salvatori, Valeria Manganelli, Alberto Ferri, Roberta Misasi, Margherita Ruoppolo;
Proteome data of neuroblastoma cells overexpressing neuroglobin.
Data Brief 41:107843.1-107843.7(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C0U0
Encyclopedic resources Wikidata; Q112930384
Proteomic databases PRIDE; PXD029012
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number9