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Cellosaurus SH-SY5Y-FLAG-NGB (CVCL_C0U0)

[Text version]
Cell line name SH-SY5Y-FLAG-NGB
Accession CVCL_C0U0
Resource Identification Initiative To cite this cell line use: SH-SY5Y-FLAG-NGB (RRID:CVCL_C0U0)
Comments Population: Caucasian.
Transfected with: HGNC; 14077; NGB (with a C-terminal 3xFLAG tag).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Omics: Deep quantitative proteome analysis.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Mutation; HGNC; 427; ALK; Simple; p.Phe1174Leu (c.3522C>A); ClinVar=VCV000217852; Zygosity=Unspecified (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0019 (SH-SY5Y)
Sex of cell Female
Age at sampling 4Y
Category Cancer cell line

PubMed=34943907; DOI=10.3390/cells10123394
Manganelli V., Salvatori I., Costanzo M., Capozzi A., Caissutti D., Caterino M., Valle C., Ferri A., Sorice M., Ruoppolo M., Garofalo T., Misasi R.
Overexpression of neuroglobin promotes energy metabolism and autophagy induction in human neuroblastoma SH-SY5Y cells.
Cells 10:3394.1-3394.18(2021)

PubMed=35128003; DOI=10.1016/j.dib.2022.107843
Costanzo M., Caterino M., Salvatori I., Manganelli V., Ferri A., Misasi R., Ruoppolo M.
Proteome data of neuroblastoma cells overexpressing neuroglobin.
Data Brief 41:107843.1-107843.7(2022)

Cell line databases/resources cancercelllines; CVCL_C0U0
Encyclopedic resources Wikidata; Q112930384
Proteomic databases PRIDE; PXD029012
Entry history
Entry creation23-Jun-2022
Last entry update05-Oct-2023
Version number5