Cellosaurus ACTOne GPR119 (CVCL_C0SS)
| Cell line name | ACTOne GPR119 |
|---|---|
| Accession | CVCL_C0SS |
| Resource Identification Initiative | To cite this cell line use: ACTOne GPR119 (RRID:CVCL_C0SS) |
| Comments | Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Dexorgen). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:19060; GPR119. Genetic integration: Method=Transduction; Gene=RGD; 2367; Cnga2 (Note=With p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C0RU (HEK293-CNG) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Web pages | Provider; Dexorgen; CB-80200-274; https://www.dexorgen.com/actone-cell-lines/ |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112929157 |
| Entry history | |
| Entry creation | 23-Jun-2022 |
| Last entry update | 10-Apr-2025 |
| Version number | 7 |