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Cellosaurus ACTOne ADORA2A (CVCL_C0S1)

[Text version]
Cell line name ACTOne ADORA2A
Accession CVCL_C0S1
Resource Identification Initiative To cite this cell line use: ACTOne ADORA2A (RRID:CVCL_C0S1)
Comments Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions).
Transfected with: RGD; 2367; Cnga2 (with p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC).
Transfected with: HGNC; 263; ADORA2A.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0RU (HEK293-CNG)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Web pages http://www.codexbiosolutions.com/wp-content/uploads/cb-80200-261.pdf
Cross-references
Encyclopedic resources Wikidata; Q112929128
Entry history
Entry creation23-Jun-2022
Last entry update29-Jun-2023
Version number4