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Cellosaurus CAL-27 2B3 (CVCL_C0RL)

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Cell line name CAL-27 2B3
Synonyms Cal27 2B3; 2B3
Accession CVCL_C0RL
Resource Identification Initiative To cite this cell line use: CAL-27 2B3 (RRID:CVCL_C0RL)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:6156; ITGB3.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Leu (c.578A>T); ClinVar=VCV000185822; Zygosity=Unspecified (from parent cell line).
Disease Tongue adenosquamous carcinoma (NCIt: C173807)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1107 (CAL-27)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=27108184; DOI=10.1016/j.bbamcr.2016.04.019
Nikolina Stojanovic, Anamaria Brozovic, Dragomira Majhen, Maja Herak Bosnar, Gerhard Fritz, Maja Osmak, Andreja Ambriovic-Ristov;
Integrin alphavbeta3 expression in tongue squamous carcinoma cells Cal27 confers anticancer drug resistance through loss of pSrc(Y418).
Biochim. Biophys. Acta 1863:1969-1978(2016)

Cross-references
Encyclopedic resources Wikidata; Q112929361
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7