Cellosaurus cell line KPB6 (CVCL

Cross-references
Cell line name	KPB6
Accession	CVCL_C0RJ
Resource Identification Initiative	To cite this cell line use: KPB6 (RRID:CVCL_C0RJ)
Comments	From: Quezada, Sergio Andres; University College London; London; United Kingdom. Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53. Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96680; Kras (Note=With p.Gly12Asp). Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Disease	Adenocarcinoma of the mouse pulmonary system (NCIt: C21771)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: C57BL/6 KrasLSL-G12D/+, Trp53flox/flox (KP).
Category	Cancer cell line
Publications	PubMed=29246442; DOI=10.1016/j.immuni.2017.11.016; PMCID=PMC5746170 Matthew A. Coelho, Sophie de Carne Trecesson, Sareena Rana, Davide Zecchin, Christopher Moore, Miriam Molina-Arcas, Philip East, Bradley Spencer-Dene, Emma Nye, Karin Barnouin, Ambrosius P. Snijders ...Show all 14 authors... , Wi S. Lai, Perry Justin Blackshear, Julian Downward; Show fewer authors Oncogenic RAS signaling promotes tumor immunoresistance by stabilizing PD-L1 mRNA. Immunity 47:1083-1099.e6(2017) CLPUB00709 Jake Yarren Henry; Innate lymphoid-macrophage crosstalk promotes lung cancer regression in response to IL-12 therapy. Thesis PhD (2019); University College London; London; United Kingdom
Encyclopedic resources	Wikidata; Q112929964
Entry history
Entry creation	23-Jun-2022
Last entry update	10-Sep-2024
Version number	6