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Cellosaurus HeLa HNRNPD-/- cl4 (CVCL_C0RI)

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Cell line name HeLa HNRNPD-/- cl4
Accession CVCL_C0RI
Resource Identification Initiative To cite this cell line use: HeLa HNRNPD-/- cl4 (RRID:CVCL_C0RI)
Comments Population: African American.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:5036; HNRNPD.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=30799487; DOI=10.1093/nar/gkz076; PMCID=PMC6486545
Luigi Alfano, Antonella Caporaso, Angela Altieri, Milena Dell'Aquila, Claudia Landi, Luca Bini, Francesca Pentimalli, Antonio Giordano;
Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation.
Nucleic Acids Res. 47:4068-4085(2019)

Cross-references
Encyclopedic resources Wikidata; Q112929704
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number7