Cellosaurus logo
expasy logo

Cellosaurus HepaRG-POR#2 (CVCL_C0R1)

[Text version]
Cell line name HepaRG-POR#2
Accession CVCL_C0R1
Resource Identification Initiative To cite this cell line use: HepaRG-POR#2 (RRID:CVCL_C0R1)
Comments Characteristics: Not completely KO for POR, can be considered as a POR knockdown cell line (PubMed=33441761).
Knockout cell: Method=CRISPR/Cas9; HGNC; 9208; POR.
Transfected with: UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatitis C infection (NCIt: C3098)
Hepatocellular carcinoma (NCIt: C3099)
Hepatocellular carcinoma (ORDO: Orphanet_88673)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0QZ (HepaRG(VC))
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=33441761; DOI=10.1038/s41598-020-79952-1
Heintze T., Klein K., Hofmann U., Zanger U.M.
Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells.
Sci. Rep. 11:1000-1000(2021)

Cross-references
Encyclopedic resources Wikidata; Q112929713
Entry history
Entry creation23-Jun-2022
Last entry update29-Jun-2023
Version number4