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Cellosaurus PC-3-R (CVCL_C0QS)

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Cell line name PC-3-R
Accession CVCL_C0QS
Resource Identification Initiative To cite this cell line use: PC-3-R (RRID:CVCL_C0QS)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: Metastatic; Bone; UBERON=UBERON_0002481.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Lys139Argfs*31 (c.414delC) (413delC); ClinVar=VCV000133281; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0035 (PC-3)
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=30244336; DOI=10.1007/s00345-018-2501-6
Hale Samli, Murat Samli, Buse Vatansever, Sena Ardicli, Nazlihan Aztopal, Deniz Dincel, Ahmet Sahin, Faruk Balci;
Paclitaxel resistance and the role of miRNAs in prostate cancer cell lines.
World J. Urol. 37:1117-1126(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C0QS
Encyclopedic resources Wikidata; Q112930250
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number6