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Cellosaurus VCaP-R (CVCL_C0QQ)

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Cell line name VCaP-R
Accession CVCL_C0QQ
Resource Identification Initiative To cite this cell line use: VCaP-R (RRID:CVCL_C0QQ)
Comments Population: Caucasian.
Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (from parent cell line).
Selected for resistance to: ChEBI; CHEBI_45863; Paclitaxel (Taxol).
Derived from site: Metastatic; Bone, vertebra; UBERON=UBERON_0002412.
Sequence variations
  • Gene fusion; HGNC; HGNC:3446; ERG + HGNC; HGNC:11876; TMPRSS2; Name(s)=TMPRSS2-ERG (from parent cell line).
  • Mutation; HGNC; HGNC:7127; MLH1; Simple; p.Ile219Val (c.655A>G); ClinVar=VCV000036557; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Homozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2235 (VCaP)
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
Publications

PubMed=30244336; DOI=10.1007/s00345-018-2501-6
Hale Samli, Murat Samli, Buse Vatansever, Sena Ardicli, Nazlihan Aztopal, Deniz Dincel, Ahmet Sahin, Faruk Balci;
Paclitaxel resistance and the role of miRNAs in prostate cancer cell lines.
World J. Urol. 37:1117-1126(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C0QQ
Encyclopedic resources Wikidata; Q112930541
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7