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Cellosaurus NCCIT-R (CVCL_C0QL)

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Cell line name NCCIT-R
Accession CVCL_C0QL
Resource Identification Initiative To cite this cell line use: NCCIT-R (RRID:CVCL_C0QL)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Omics: Proteomics; Quantitative.
Sequence variations
  • Mutation; HGNC; HGNC:6844; MAP2K4; Simple; p.Lys309Asn (c.927G>C); Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg173Pro (c.518G>C); ClinVar=VCV000185195; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val272Cysfs*73 (c.814delG); Zygosity=Homozygous (from parent cell line).
Disease Testicular embryonal carcinoma (NCIt: C6341)
Non-central nervous system-localized embryonal carcinoma (ORDO: Orphanet_289362)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1451 (NCC-IT)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
Publications

PubMed=35084545; DOI=10.1007/s00345-022-03936-1; PMCID=PMC8921118
Alexander Fichtner, Hanibal Bohnenberger, Omar Elakad, Annika Richter, Christof Lenz, Christoph Oing, Philipp Strobel, Stefan Kueffer, Daniel Nettersheim, Felix Bremmer;
Proteomic profiling of cisplatin-resistant and cisplatin-sensitive germ cell tumour cell lines using quantitative mass spectrometry.
World J. Urol. 40:373-383(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C0QL
Encyclopedic resources Wikidata; Q112930165
Proteomic databases PRIDE; PXD030251
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number6