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Cellosaurus GL-40 (CVCL_C0Q1)

[Text version]
Cell line name GL-40
Accession CVCL_C0Q1
Resource Identification Initiative To cite this cell line use: GL-40 (RRID:CVCL_C0Q1)
Comments Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Disease Canine leukemia (NCIt: C128120)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Breed/subspecies: German Shepherd; VBO=VBO_0200577.
Hierarchy Parent: CVCL_L352 (GL-1 [Dog leukemia])
Sex of cell Male
Age at sampling 9Y
Category Cancer cell line
Publications

PubMed=23363222; DOI=10.1111/jvp.12039
Zandvliet M., Teske E., Chapuis T., Fink-Gremmels J., Schrickx J.A.
Masitinib reverses doxorubicin resistance in canine lymphoid cells by inhibiting the function of P-glycoprotein.
J. Vet. Pharmacol. Ther. 36:583-587(2013)

PubMed=24975508; DOI=10.1016/j.tiv.2014.06.004
Zandvliet M., Teske E., Schrickx J.A.
Multi-drug resistance in a canine lymphoid cell line due to increased P-glycoprotein expression, a potential model for drug-resistant canine lymphoma.
Toxicol. In Vitro 28:1498-1506(2014)

Cross-references
Encyclopedic resources Wikidata; Q112929584
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number6