Cellosaurus cell line GL-40 (CVCL

Cross-references
Cell line name	GL-40
Accession	CVCL_C0Q1
Resource Identification Initiative	To cite this cell line use: GL-40 (RRID:CVCL_C0Q1)
Comments	Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin). Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. Cell type: B-cell; CL=CL_0000236.
Disease	Canine leukemia (NCIt: C128120)
Species of origin	Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615) Breed/subspecies: German Shepherd; VBO=VBO_0200577.
Hierarchy	Parent: CVCL_L352 (GL-1 [Dog leukemia])
Sex of cell	Male
Age at sampling	9Y
Category	Cancer cell line
Publications	PubMed=23363222; DOI=10.1111/jvp.12039 Maurice Zandvliet, Erik Teske, Tom Chapuis, Johanna Fink-Gremmels, Johannes Antonius Schrickx; Masitinib reverses doxorubicin resistance in canine lymphoid cells by inhibiting the function of P-glycoprotein. J. Vet. Pharmacol. Ther. 36:583-587(2013) PubMed=24975508; DOI=10.1016/j.tiv.2014.06.004 Maurice Zandvliet, Erik Teske, Johannes Antonius Schrickx; Multi-drug resistance in a canine lymphoid cell line due to increased P-glycoprotein expression, a potential model for drug-resistant canine lymphoma. Toxicol. In Vitro 28:1498-1506(2014)
Encyclopedic resources	Wikidata; Q112929584
Entry history
Entry creation	23-Jun-2022
Last entry update	19-Dec-2024
Version number	6