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Cellosaurus PC12 cA4 (CVCL_C0PZ)

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Cell line name PC12 cA4
Synonyms TRalpha-1-PC12; TRalpha1-expressing PC12
Accession CVCL_C0PZ
Resource Identification Initiative To cite this cell line use: PC12 cA4 (RRID:CVCL_C0PZ)
Comments Genetic integration: Method=Transduction; Gene=CGNC; 155; THRA.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Disease Rat adrenal gland pheochromocytoma (NCIt: C121568)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS_0000603.
Hierarchy Parent: CVCL_C0PY (PC12 6c)
Children:
CVCL_C0Q0 (PC-DR-LUC)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=8385673; DOI=10.1083/jcb.121.2.423; PMCID=PMC2200090
Alberto Munoz, Christopher Wrighton, Barbara Seliger, Juan Bernal, Hartmut Beug;
Thyroid hormone receptor/c-erbA: control of commitment and differentiation in the neuronal/chromaffin progenitor line PC12.
J. Cell Biol. 121:423-438(1993)

PubMed=17532181; DOI=10.1016/j.tiv.2007.03.020
Mary-Line Jugan, Maya Levy-Bimbot, Martine Pomerance, Sara Tamisier-Karolak, Jean-Paul Blondeau, Yves Levi;
A new bioluminescent cellular assay to measure the transcriptional effects of chemicals that modulate the alpha-1 thyroid hormone receptor.
Toxicol. In Vitro 21:1197-1205(2007)

Cross-references
Encyclopedic resources Wikidata; Q112930262
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number9