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Cellosaurus CBIGi001-A-2 (CVCL_C0K0)

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Cell line name CBIGi001-A-2
Synonyms PINK1-KO; AIW002-02/PINK1-KO; PINK1-KO/AIW002-02
Accession CVCL_C0K0
Resource Identification Initiative To cite this cell line use: CBIGi001-A-2 (RRID:CVCL_C0K0)
Comments From: Clinical Biospecimen Imaging and Genetic (C-BIG) Repository, Montreal Neurological Institute, McGill University; Montreal; Canada.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:14581; PINK1.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0JY (CBIGi001-A)
Sex of cell Male
Age at sampling 37Y
Category Induced pluripotent stem cell
Web pages Info; McGill; -; https://www.mcgill.ca/neuro/files/neuro/pink1-ko-aiw002-02-datasheet.pdf
Provider; C-BIG; -; https://cbigr-open.loris.ca/C-BIG_ipsc_catalog_august_2023.pdf
Publications

PubMed=35561458; DOI=10.1016/j.scr.2022.102806
Carol Xiu-Qing Chen, Zhi-Peng You, Narges Abdian, Julien Sirois, Irina Shlaifer, Mahdieh Tabatabaei, Marie-Noelle Boivin, Lydiane Gaborieau, Jason Karamchandani, Lenore K. Beitel, Edward A. Fon, Thomas M. Durcan;
Generation of homozygous PRKN, PINK1 and double PINK1/PRKN knockout cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing.
Stem Cell Res. 62:102806-102806(2022)

Cross-references
Cell line databases/resources hPSCreg; CBIGi001-A-2
Biological sample resources BioSamples; SAMEA12866579
Encyclopedic resources Wikidata; Q112929368
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number6