Cellosaurus logo
expasy logo

Cellosaurus 293EL-APP-/- (CVCL_C0I8)

[Text version]
Cell line name 293EL-APP-/-
Accession CVCL_C0I8
Resource Identification Initiative To cite this cell line use: 293EL-APP-/- (RRID:CVCL_C0I8)
Comments Characteristics: Using CRISPR/Cas9 TMEM192 was C-terminally tagged on both alleles with a 3xHA epitope.
Knockout cell: Method=CRISPR/Cas9; HGNC; 620; APP.
Transfected with: HGNC; 3185; EEA1 (with a N-terminal FLAG tag).
Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0I7 (293EL)
Children:
CVCL_C0I9 (293EL-APP*)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

DOI=10.1101/2022.03.31.486371
Park H., Yu Q., Hundley F.V., Overmyer K., Serrano L., Paulo J.A., Paoli J.C., Swarup S., Coon J.J., Gygi S.P., Harper J.W.
Early endosome capture proteomics and its application to amyloid precursor protein intramembrane processing by beta and gamma-secretases.
bioRxiv 2022:03.31.486371-03.31.486371(2022)

Cross-references
Encyclopedic resources Wikidata; Q112926923
Entry history
Entry creation23-Jun-2022
Last entry update05-Oct-2023
Version number5