Cellosaurus 293EL-APP-/- (CVCL_C0I8)
| Cell line name | 293EL-APP-/- | |
|---|---|---|
| Accession | CVCL_C0I8 | |
| Resource Identification Initiative | To cite this cell line use: 293EL-APP-/- (RRID:CVCL_C0I8) | |
| Comments | Characteristics: Using CRISPR/Cas9 TMEM192 was C-terminally tagged on both alleles with a 3xHA epitope (from parent cell line). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:620; APP. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:3185; EEA1 (Note=With a N-terminal FLAG tag). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. | |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | |
| Hierarchy | Parent: CVCL_C0I7 (293EL) Children:
| |
| Sex of cell | Female | |
| Age at sampling | Fetus | |
| Category | Transformed cell line | |
| Publications | PubMed=36245040; DOI=10.1038/s41467-022-33881-x; PMCID=PMC9573879 | |
| Cross-references | ||
| Encyclopedic resources | Wikidata; Q112926923 | |
| Entry history | ||
| Entry creation | 23-Jun-2022 | |
| Last entry update | 14-Aug-2025 | |
| Version number | 8 | |