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Cellosaurus HEK293::TMEM192-3xHA APP-/- (CVCL_C0I6)

[Text version]
Cell line name HEK293::TMEM192-3xHA APP-/-
Synonyms 293L-APP-/-
Accession CVCL_C0I6
Resource Identification Initiative To cite this cell line use: HEK293::TMEM192-3xHA APP-/- (RRID:CVCL_C0I6)
Comments Characteristics: Using CRISPR/Cas9 TMEM192 was C-terminally tagged on both alleles with a 3xHA epitope.
Knockout cell: Method=CRISPR/Cas9; HGNC; 620; APP.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C0I5 (HEK293::TMEM192-3xHA)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

DOI=10.1101/2022.03.31.486371
Park H., Yu Q., Hundley F.V., Overmyer K., Serrano L., Paulo J.A., Paoli J.C., Swarup S., Coon J.J., Gygi S.P., Harper J.W.
Early endosome capture proteomics and its application to amyloid precursor protein intramembrane processing by beta and gamma-secretases.
bioRxiv 2022:03.31.486371-03.31.486371(2022)

Cross-references
Encyclopedic resources Wikidata; Q112926930
Entry history
Entry creation23-Jun-2022
Last entry update30-Jan-2024
Version number6