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Cellosaurus HEK293 NDUSF2 KO (CVCL_C0D2)

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Cell line name HEK293 NDUSF2 KO
Synonyms HEK293deltaNDUFS2; HEK293deltandufs2
Accession CVCL_C0D2
Resource Identification Initiative To cite this cell line use: HEK293 NDUSF2 KO (RRID:CVCL_C0D2)
Comments Group: Patented cell line.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:7708; NDUFS2.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

Patent=WO2021067415A1
Aloka B. Bandara, David A. Brown;
NDUFS2 subunit knockout human cell line.
Patent number WO2021067415A1, 08-Apr-2021

PubMed=33744462; DOI=10.1016/j.mito.2021.03.003; PMCID=PMC8113094
Aloka B. Bandara, Joshua C. Drake, Carissa C. James, James W. Smyth, David A. Brown;
Complex I protein NDUFS2 is vital for growth, ROS generation, membrane integrity, apoptosis, and mitochondrial energetics.
Mitochondrion 58:160-168(2021)

Cross-references
Cell line collections (Providers) ABM; T3224
CancerTools; 156497
Ximbio; 156497
Encyclopedic resources Wikidata; Q112929670
Entry history
Entry creation23-Jun-2022
Last entry update14-Aug-2025
Version number8