Cellosaurus cell line UPCI-SCC-182 (CVCL

Cellosaurus UPCI-SCC-182 (CVCL_C060)

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Cell line name

UPCI-SCC-182

Synonyms

UPCI:SCC182; SCC-182; SCC182

Accession

CVCL_C060

Resource Identification Initiative

To cite this cell line use: UPCI-SCC-182 (RRID:CVCL_C060)

Comments

Population: Caucasian.
Doubling time: ~60-80 hours, ~100 hours (Note=After recovery from liquid nitrogen freezing) (DSMZ=ACC-887).
Derived from site: In situ; Oral cavity, retromolar trigone; UBERON=UBERON_0012376.

Sequence variations

Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu294Ter (c.880G>T); ClinVar=VCV000379471; Zygosity=Unspecified (PubMed=12872257).

Disease

Retromolar trigone squamous cell carcinoma (NCIt: C8172)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

71Y

Category

Cancer cell line

STR profile

Source(s): DSMZ=ACC-887

Markers:

Amelogenin	X,Y
CSF1PO	11
D2S1338	24,25
D3S1358	17
D5S818	13
D7S820	11
D8S1179	13,14
D13S317	12
D16S539	13
D18S51	13,19
D19S433	14,15
D21S11	31
FGA	21,28
Penta D	13
Penta E	15,17
TH01	7
TPOX	8,9
vWA	17,18

Publications

PubMed=12872257; DOI=10.1002/humu.10248
Cheryl A. Telmer, Ji-Yan An, David E. Malehorn, Xue-Mei Zeng, Susanne M. Gollin, Chandramohan S. Ishwad, Jonathan W. Jarvik;
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
Jason S. White, Joel L. Weissfeld, Camille C.R. Ragin, Karen M. Rossie, Christa Lese Martin, Michele Shuster, Chandramohan S. Ishwad, John C. Law, Eugene Nicholas Myers, Jonas T. Johnson, Susanne M. Gollin;
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=24142626; DOI=10.1002/gcc.22115; PMCID=PMC5520977
Rahul Atul Parikh, Leonard J. Appleman, Julie E. Bauman, Madhav Sankunny, Dale W. Lewis, Anda Vlad, Susanne M. Gollin;
Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.
Genes Chromosomes Cancer 53:25-37(2014)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-887

Cell line databases/resources

cancercelllines; CVCL_C060
DSMZCellDive; ACC-887

Encyclopedic resources

Wikidata; Q54991689

Polymorphism and mutation databases

IARC_TP53; 18368

Entry history

Entry creation

06-Jun-2012

Last entry update

19-Dec-2024

Version number