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Cellosaurus UPCI-SCC-032 (CVCL_C029)

[Text version]
Cell line name UPCI-SCC-032
Synonyms UPCI:SCC032; SCC032
Accession CVCL_C029
Resource Identification Initiative To cite this cell line use: UPCI-SCC-032 (RRID:CVCL_C029)
Comments Population: Caucasian.
Doubling time: ~50-60 hours (DSMZ=ACC-864).
Derived from site: In situ; Oral cavity, retromolar trigone; UBERON=UBERON_0012376.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Leu289fs (c.867_868del2); Zygosity=Unspecified (PubMed=12872257).
Disease Retromolar trigone squamous cell carcinoma (NCIt: C8172)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-864

Markers:
AmelogeninX
CSF1PO11
D2S133824
D3S135815
D5S81813
D7S82011,14
D8S117913
D13S3178,11
D16S5399,13
D18S5117
D19S43312,13
D21S1129,31
FGA22,22.2
Penta D11,12
Penta E12,15
TH017,9
TPOX8,11
vWA16

Run an STR similarity search on this cell line
Publications

PubMed=12872257; DOI=10.1002/humu.10248
Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M., Ishwad C.S., Jarvik J.W.
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001
White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L., Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T., Gollin S.M.
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003
Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W., Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

PubMed=24142626; DOI=10.1002/gcc.22115
Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W., Vlad A., Gollin S.M.
Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.
Genes Chromosomes Cancer 53:25-37(2014)

Cross-references
Cell line collections (Providers) DSMZ; ACC-864
Cell line databases/resources DSMZCellDive; ACC-864
Encyclopedic resources Wikidata; Q54991572
Polymorphism and mutation databases IARC_TP53; 18352
Entry history
Entry creation06-Jun-2012
Last entry update02-May-2024
Version number13