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Cellosaurus UPCI-SCC-003 (CVCL_C025)

[Text version]
Cell line name UPCI-SCC-003
Synonyms UPCI:SCC003; UPCISCC003; SCC003
Accession CVCL_C025
Resource Identification Initiative To cite this cell line use: UPCI-SCC-003 (RRID:CVCL_C025)
Comments Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Doubling time: ~45 hours (DSMZ=ACC-863).
Omics: Genomics; DNA methylation analysis.
Omics: Proteomics; Expression; Reverse-phase protein array.
Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-863

Markers:
AmelogeninX
CSF1PO11
D2S133820
D3S135814
D5S81811
D7S8208,14
D8S11798
D13S31711
D16S5399
D18S5113
D19S43314
D21S1129,30
FGA25
Penta D11,13
Penta E12
TH018,9
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Web pages Info; MCLP; -; https://tcpaportal.org/mclp/
Publications

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692
Jason S. White, Joel L. Weissfeld, Camille C.R. Ragin, Karen M. Rossie, Christa Lese Martin, Michele Shuster, Chandramohan S. Ishwad, John C. Law, Eugene Nicholas Myers, Jonas T. Johnson, Susanne M. Gollin;
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065
Christa Lese Martin, Shalini C. Reshmi, Thomas Ried, William Gottberg, John W. Wilson, Jaya K. Reddy, Poornima Khanna, Jonas T. Johnson, Eugene Nicholas Myers, Susanne M. Gollin;
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

PubMed=23419152; DOI=10.1186/gm419; PMCID=PMC3706778
Matthias Lechner, Tim R. Fenton, James West, Gareth Wilson, Andrew Feber, Stephen Henderson, Christina Thirlwell, Harpreet K. Dibra, Amrita Jay, Lee M. Butcher, Ankur Ravinarayana Chakravarthy ...Show all 19 authors... , Fiona Gratrix, Nirali Patel, Francis Vaz, Paul O'Flynn, Nicholas Kalavrezos, Andrew Erich Teschendorff, Chris Boshoff, Stephan Beck; Show fewer authors
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Genome Med. 5:15.1-15.16(2013)

PubMed=24403267; DOI=10.1002/cam4.151; PMCID=PMC3892398
Hisato Kawakami, Isamu Okamoto, Kyoichi Terao, Kazuko Sakai, Minoru Suzuki, Shinya Ueda, Kaoru Tanaka, Kiyoko Kuwata, Yume Morita, Koji Ono, Kazuto Nishio ...Show all 14 authors... , Yasumasa Nishimura, Katsumi Doi, Kazuhiko Nakagawa; Show fewer authors
Human papillomavirus DNA and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma.
Cancer Med. 2:933-941(2013)

PubMed=24142626; DOI=10.1002/gcc.22115; PMCID=PMC5520977
Rahul Atul Parikh, Leonard J. Appleman, Julie E. Bauman, Madhav Sankunny, Dale W. Lewis, Anda Vlad, Susanne M. Gollin;
Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.
Genes Chromosomes Cancer 53:25-37(2014)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005; PMCID=PMC5501076
Jun Li, Wei Zhao, Rehan Akbani, Wen-Bin Liu, Zhen-Lin Ju, Shi-Yun Ling, Christopher P. Vellano, Paul Roebuck, Qing-Hua Yu, A. Karina Eterovic, Lauren Averett Byers ...Show all 25 authors... , Michael A. Davies, Wan-Leng Deng, Y.N. Vashisht Gopal, Guo Chen, Erika Maria von Euw, Dennis Joseph Slamon, Dylan Conklin, John Victor Heymach, Adi F. Gazdar, John D. Minna, Jeffrey N. Myers, Yi-Ling Lu, Gordon B. Mills, Han Liang; Show fewer authors
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-863
Cell line databases/resources DSMZCellDive; ACC-863
Encyclopedic resources Wikidata; Q54991560
Gene expression databases GEO; GSM937836
GEO; GSM937837
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number14