Cellosaurus cell line Shef6.1 (CVCL

Cellosaurus Shef6.1 (CVCL_BW73)

Cross-references
Cell line name	Shef6.1
Synonyms	Shef 6-1
Accession	CVCL_BW73
Resource Identification Initiative	To cite this cell line use: Shef6.1 (RRID:CVCL_BW73)
Comments	Group: Clinical grade pluripotent cell line. From: University of Sheffield; Sheffield; United Kingdom. Registration: Swiss research registry; BAG-hES-IMP-0060. Registration: UK Stem Cell Bank (UKSCB); C-18-002, Steering comm. appl. SCSC14-35. Omics: Genomics; Whole exome sequencing. Omics: Variations; CNV analysis. Omics: Variations; SNP array analysis. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9793 (Shef6)
Sex of cell	Female
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Publications	PubMed=26607962; DOI=10.1038/srep17258; PMCID=PMC4660465 Maurice A. Canham, Amy Lynnette Van Deusen, Daniel Roy Brison, Paul Alexandre De Sousa, Janet M. Downie, Liani Gasparini Devito, Zoe A. Hewitt, Dusko Ilic, Susan J. Kimber, Harry D. Moore, Helen Murray, Tilo Kunath; The molecular karyotype of 25 clinical-grade human embryonic stem cell lines. Sci. Rep. 5:17258.1-17258.13(2015) PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175 Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations. Nature 545:229-233(2017)
Encyclopedic resources	Wikidata; Q54953283
Entry history
Entry creation	13-Jul-2016
Last entry update	14-Aug-2025
Version number	11