Cellosaurus logo
expasy logo

Cellosaurus McWT1 (CVCL_B9UX)

[Text version]
Cell line name McWT1
Synonyms 9v; L9
Accession CVCL_B9UX
Resource Identification Initiative To cite this cell line use: McWT1 (RRID:CVCL_B9UX)
Comments Omics: Transcriptomics; Microarray.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Melanocyte of skin; CL=CL_1000458.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6J.
Sex of cell Male
Age at sampling 1D
Category Spontaneously immortalized cell line
Publications

PubMed=18006687; DOI=10.1101/gad.450107; PMCID=PMC2049194
Delmas V., Beermann F., Martinozzi S., Carreira S., Ackermann J., Kumasaka M., Denat L., Goodall J., Luciani F., Viros A., Demirkan N., Bastian B.C., Goding C.R., Larue L.
Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development.
Genes Dev. 21:2923-2935(2007)

PubMed=31251472; DOI=10.1111/pcmr.12807
Petit V., Raymond J., Alberti C., Pouteaux M., Gallagher S.J., Nguyen M.Q., Aplin A.E., Delmas V., Larue L.
C57BL/6 congenic mouse NRAS(Q61K) melanoma cell lines are highly sensitive to the combination of Mek and Akt inhibitors in vitro and in vivo.
Pigment Cell Melanoma Res. 32:829-841(2019)

Cross-references
Encyclopedic resources Wikidata; Q112930097
Entry history
Entry creation23-Jun-2022
Last entry update10-Apr-2025
Version number5